4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate

Base Information

• Chemical Name: 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate
• CAS No.: 203627-33-2
• Molecular Formula: C₁₈H₁₂F₃NO₄
• Molecular Weight: 363.293
• Mol file: 203627-33-2.mol

Synonyms:4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate

Chemical Property of 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate

There total 1 articles about 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-(p-methoxybenzoyl)-N-(phenyl)glycine (35876-73-4) + trifluoroacetic anhydride (407-25-0) → 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate (203627-33-2)

Guidance literature:

In ethyl acetate; at 0 ℃; for 3h;

DOI:10.3987/COM-16-13551

Reference yield: 99.0%

[(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) + 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate (203627-33-2) → 6-(4-methoxyphenyl)-5-((4-methylphenyl)sulfonyl)-7-phenylimidazo[1,5-a]pyrazin-8(7H)-one

Guidance literature:

[(p-methylphenyl)sulfonylmethyl]isonitrile; With oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate; In N,N-dimethyl-formamide; at 0 ℃; for 5h;

DOI:10.3987/COM-16-13551

Reference yield: 88.0%

phenylhydrazine (100-63-0) + 4-trifluoroacetyl-2-(4-methoxyphenyl)-3-phenyl-1,3-oxazolium-5-olate (203627-33-2) → 6-trifluoromethyl-1,4,5,6-tetrahydro-3-(4-methoxyphenyl)-1,4-diphenyl-1,2,4-triazin-6-ol

Guidance literature:

In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(97)10712-2

upstream raw materials:

N-(p-methoxybenzoyl)-N-(phenyl)glycine

trifluoroacetic anhydride