Sodium naphthalene-1-acetate

Base Information

• Chemical Name: Sodium naphthalene-1-acetate
• CAS No.: 61-31-4
• Molecular Formula: C12H9NaO2
• Molecular Weight: 208.192
• Hs Code.: 29163990
• Mol file: 61-31-4.mol

Synonyms:1-Naphthaleneaceticacid, sodium salt (8CI,9CI);1-Naphthylacetic acid sodium salt;Pomonit;Pomonit R 10;Radi-Stim;Sodium 1-naphthaleneacetate;Sodium 1-naphthylacetate;Sodium a-naphthaleneacetate;Sodium a-naphthylacetate;Stik;Stik(growth regulator);a Naphthylacetic acid sodium salt;1-Naphthaleneacetic acid,sodium salt;

Chemical Property of Sodium naphthalene-1-acetate

Chemical Property:

• Vapor Pressure: 3.13E-06mmHg at 25°C
• Melting Point: 134.5-135.5oC
• Boiling Point: 373.2 °C at 760 mmHg
• Flash Point: 270.1 °C
• PSA: 40.13000
• LogP: 1.13220
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility.: almost transparency

Purity/Quality:

99% ^*data from raw suppliers

Sodium 1-Naphthaleneacetate >96.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sodium naphthalene-1-acetate

There total 2 articles about Sodium naphthalene-1-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.92%

carbon monoxide (201230-82-2) + 1-Chloromethylnaphthalene (86-52-2) → sodium salt of 1-naphthylacetic acid (61-31-4)

Guidance literature:

With sodium hydroxide; at 65 ℃; for 10h; under 16501.7 Torr; Pressure; Time; Temperature; Autoclave;

Reference yield:

→ sodium salt of 1-naphthylacetic acid (61-31-4)

Guidance literature:

Reference yield: 96.0%

2,4,6-trifluorophenylglyoxylic acid + sodium salt of 1-naphthylacetic acid (61-31-4) → 3-(2,4,6-trifluorophenyl)-4-(1-naphthyl)furan-2,5-dione

Guidance literature:

With acetic anhydride; for 2h; Inert atmosphere; Reflux;

upstream raw materials:

carbon monoxide

1-Chloromethylnaphthalene

Downstream raw materials:

naphthalen-1-yl-acetyl chloride

Refernces

Potential psychotropic and anthistamine agents: 1- and 3-alkyl-9-(3-dimethylaminopropylidene)- thioxanthenes and 3-alkyl-11-piperazino-10,11-dihydrodibenzo[b,f]thiepins

10.1135/cccc19823134

The research explores the synthesis and pharmacological properties of various thioxanthene and dibenzo[b,f]thiepin derivatives. The study involves the use of chemicals such as 3-methylthiophenol, 3-ethylthiophenol, 2-iodobenzoic acid, (2-iodophenyl)acetic acid, potassium hydroxide, copper, sulfuric acid, polyphosphoric acid, 3-dimethylaminopropylmagnesium chloride, and various piperazine derivatives. These chemicals are used in a series of reactions to produce compounds with potential antihistamine and psychotropic activities. The synthesized compounds are tested for their pharmacological effects, including antihistamine activity, central depressant effects, cataleptic activity, and antireserpine activity. The research aims to investigate the impact of substituents in unusual positions on the pharmacological profiles of these compounds, with potential applications in treating conditions like gastric hyperacidity, ulcers, and central nervous system disorders.