2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

Base Information

Chemical Name:2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester
CAS No.:1123546-52-0
Molecular Formula:C₂₅H₃₁F₃N₄O₆
Molecular Weight:540.54
Hs Code.:

Synonyms:2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

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Chemical Property of 2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

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Technology Process of 2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

There total 1 articles about 2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1123546-35-9
2-(3-{N'-[3-(3,4-dimethoxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

: 1123546-52-0
2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

Guidance literature:: With piperidine; In N,N-dimethyl-formamide; at 20 ℃; for 1.3h;
DOI:10.1016/j.bmcl.2008.11.012

Reference yield: 41.0%

: 1123546-52-0
2-(3-{N'-[2-amino-3-(3,4-dimethoxyphenyl)propionyl]hydrazino}-4,4,4-trifluorobutyrylamino)-3-phenylpropionic acid methyl ester

: 32852-81-6
(3-phenoxyphenyl)acetic acid

: 1123546-02-0
2-[3-(N'-{3-(3,4-dimethoxyphenyl)-2-[2-(3-phenoxyphenyl)acetylamino]propionyl}hydrazino)-4,4,4-trifluorobutyrylamino]-3-phenylpropionic acid methyl ester

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.bmcl.2008.11.012