β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)

Base Information

• Chemical Name: β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)
• CAS No.: 228412-71-3
• Molecular Formula: C₂₀H₂₁NO₁₄
• Molecular Weight: 499.385
• Hs Code.: 2940000080
• Mol file: 228412-71-3.mol

Synonyms:(2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(((4-nitrophenoxy)carbonyl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Chemical Property of β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)

Chemical Property:

• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

β-D-GlucopyranuronicAcidMethylEster2,3,4-Triacetate1-(4-NitrophenylCarbonate) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: p-Nitrophenyl Carbonate 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is used in the synthesis of Varenicline Carbamoyl metabolite. β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate) is used in the addition of protected Glucopyranuronic Acid.

Technology Process of β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)

There total 10 articles about β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

methyl 2,3,4-tri-O-acetyl-D-glucopyranuronate (72692-06-9,73464-50-3,3082-95-9) + 4-Nitrophenyl chloroformate (7693-46-1) → C20H21NO14 + (2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(((4-nitrophenoxy)carbonyl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (228412-71-3)

Guidance literature:

With triethylamine; optical yield given as %de; stereoselective reaction;

DOI:10.1021/jo200238d

Reference yield: 77.12%

bis-(p-nitrophenyl) carbonate (5070-13-3) + 2,3,4-Tri-O-acetyl-β-D-glucopyranuronic acid methylester (3082-95-9,72692-06-9,73464-50-3) → (2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(((4-nitrophenoxy)carbonyl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (228412-71-3)

Guidance literature:

With triethylamine; In dichloromethane; at 15 ℃; for 4h; Time; Reagent/catalyst; Solvent; Temperature;

Reference yield: 77.0%

bis-(p-nitrophenyl) carbonate (5070-13-3) + methyl 2,3,4-tri-O-acetyl-D-glucopyranuronate (72692-06-9,73464-50-3,3082-95-9) → (2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(((4-nitrophenoxy)carbonyl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (228412-71-3)

Guidance literature:

With triethylamine; In dichloromethane; for 0.5h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/jo200238d

upstream raw materials:

2,3,4-Tri-O-acetyl-β-D-glucopyranuronic acid methylester

4-Nitrophenyl chloroformate

methyl (benzyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)uronate

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 228412-71-3 β-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Triacetate 1-(4-Nitrophenyl Carbonate)

Send

Send

Metric Ton KG G Pound L ML

Send

Send