Iminodiacetic acid

Base Information

• Chemical Name: Iminodiacetic acid
• CAS No.: 142-73-4
• Deprecated CAS: 57759-17-8,1404190-36-8,1404190-36-8
• Molecular Formula: C4H7NO4
• Molecular Weight: 133.104
• Hs Code.: 29224995
• European Community (EC) Number: 205-555-4
• NSC Number: 18467
• UNII: XQM2L81M8Z
• DSSTox Substance ID: DTXSID2027098
• Nikkaji Number: J386G
• Wikipedia: Iminodiacetic_acid
• Wikidata: Q409357
• Metabolomics Workbench ID: 41521
• ChEMBL ID: CHEMBL461164
• Mol file: 142-73-4.mol

Synonyms:aminodiacetic acid;imidodiacetic acid;iminodiacetic acid;iminodiacetic acid, calcium salt (1:1);iminodiacetic acid, disodium salt;iminodiacetic acid, sodium salt

Chemical Property of Iminodiacetic acid

Chemical Property:

• Appearance/Colour: white or yellowish crystalline powder
• Vapor Pressure: 1.65E-06mmHg at 25°C
• Melting Point: 243 °C (dec.)(lit.)
• Refractive Index: 1.501
• Boiling Point: 370.6 °C at 760 mmHg
• PKA: 2.98, 9.89(at 25℃)
• Flash Point: 177.9 °C
• PSA: 86.63000
• Density: 1.436 g/cm³
• LogP: -0.86390
• Storage Temp.: Store below +30°C.
• Solubility.: 42g/l
• Water Solubility.: 2.43 g/100 mL (5 ºC)
• XLogP3: -3.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 133.03750770
• Heavy Atom Count: 9
• Complexity: 108

Purity/Quality:

99% ^*data from raw suppliers

Iminodiacetic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Chelating Agents
• Canonical SMILES: C(C(=O)O)NCC(=O)O
• Uses: Iminodiacetic acid can be used:In the preparation of iminodiacetic acid (IDA)-type adsorbent for protein purification.As a catalyst along with iron (FeCl3) complexes for methyl methacrylate (MMA) polymerization. In the preparation of chelating resins with glycidyl methacrylate for the selective removal and recovery of metal ions from industrial waste water.As a reagent for the preparation of pinene-derived iminodiacetic acid (PIDA), which is in turn used as a ligand for the synthesis of diastereoselective oxiranyl C(sp3) boronates from the corresponding olefins.In the surface functionalization of multi-walled carbon nanotubes (MWCNTs) which is further utilized as a sorbent for the separation of heavy metal ions.

Technology Process of Iminodiacetic acid

There total 52 articles about Iminodiacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.25%

iminodiacetonitrile (628-87-5) → iminodiacetic acid (142-73-4)

Guidance literature:

With sodium hydroxide; at 60 - 65 ℃; for 1h; Time;

Reference yield: 96.0%

2,2'-iminobis[ethanol] (111-42-2) → iminodiacetic acid (142-73-4)

Guidance literature:

With sodium hydroxide; In water; at 160 ℃; for 0.5h; Reagent/catalyst; Temperature; Catalytic behavior;

DOI:10.1016/j.catcom.2020.106043

Reference yield: 73.0%

iminodiacetonitrile (628-87-5) → α-(cyanomethylamino)acetic acid + iminodiacetic acid (142-73-4)

Guidance literature:

With Sphingomonas wittichii nitrilase NIT₁₅₈; water; In aq. phosphate buffer; at 37 ℃; for 24h; pH=7.3; pH-value; Temperature; Solvent; enantiospecific reaction; Enzymatic reaction;

DOI:10.1002/adsc.201201098

upstream raw materials:

formaldehyd

potassium cyanide

aminomalonic acid diethyl ester

methanediyldiimino-tetra-acetonitrile

Downstream raw materials:

(trans-2-Hydroxy-cyclohexylimino)-di-essigsaeure

1-oxy-2,6-di((N,N-biscarboxymethyl)aminomethyl)-4-chlorbenzene

ethylenediaminetetraacetic acid

2,2',2,2'-(((2-hydroxy-5-methyl-1,3-phenylene)bis(methylene))bis(azanetriyl))tetraacetic acid

Refernces

• 1、 Tetenbaum,Stone. "". . p. 1699. Retrieved 1970.
• 2、 Chen, Li,Duan, Zhengkang,Guo, Dongjie,Qiu, Tian,Ren, Shiyu,Wang, Yongsheng,Wu, Yingying,Xu, Weixiang,Zhang, Xinping. "Highly efficient and stable bicomponent cobalt oxide-copper catalysts for dehydrogenation". . . Retrieved 2020.
• 3、 Tomita et al.. "". . p. 138. Retrieved 1965.
• 4、 Rayavarapu, Pratima,Shah, Shikha,Sunder, Avinash Vellore,Wangikar, Pramod P.. "Expanding the repertoire of nitrilases with broad substrate specificity and high substrate tolerance for biocatalytic applications". . p. 289 - 296. Retrieved 2020/05/18.