(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Base Information

Chemical Name:(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane
CAS No.:1276045-74-9
Molecular Formula:C₂₀H₂₄O₂S
Molecular Weight:328.475
Hs Code.:

Synonyms:(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Suppliers and Price of (Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

There total 5 articles about (Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 64-17-5
ethanol

: 52999-15-2
4-(p-methoxyphenyl)-3-butyn-1-ol

: 33775-94-9
2-(methylthio)iodobenzene

: 1276045-74-9
(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Guidance literature:: ethanol; 4-(p-methoxyphenyl)-3-butyn-1-ol; With toluene-4-sulfonic acid; at 120 ℃; for 0.5h; Microwave irradiation;

With toluene-4-sulfonic acid hydrazide; at 50 ℃; for 0.25h; Microwave irradiation;

2-(methylthio)iodobenzene; With dichloro bis(acetonitrile) palladium(II); lithium tert-butoxide; XPhos; In 1,4-dioxane; at 90 ℃; for 1h; stereoselective reaction;
DOI:10.1016/j.tetlet.2010.12.093

Reference yield:

: C₂₀H₂₆N₂O₄S

: 33775-94-9
2-(methylthio)iodobenzene

: 1276045-74-9
(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Guidance literature:: With dichloro bis(acetonitrile) palladium(II); lithium tert-butoxide; XPhos; In 1,4-dioxane; at 90 ℃; for 1h; optical yield given as %de; stereoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201101735

Reference yield:

: 52999-15-2
4-(p-methoxyphenyl)-3-butyn-1-ol

: 1276045-74-9
(Z)-{2-[4-ethoxy-1-(4-methoxyphenyl)but-1-en-1-yl]phenyl}(methyl)sulfane

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / 0.5 h / 120 °C / Microwave irradiation; Inert atmosphere

2: 0.25 h / 50 °C / Microwave irradiation; Inert atmosphere

3: dichloro bis(acetonitrile) palladium(II); lithium tert-butoxide; XPhos / 1,4-dioxane / 1 h / 90 °C / Inert atmosphere

With dichloro bis(acetonitrile) palladium(II); toluene-4-sulfonic acid; lithium tert-butoxide; XPhos; In 1,4-dioxane;
DOI:10.1002/ejoc.201101735