(R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride

Base Information

Chemical Name:(R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride
CAS No.:900176-10-5
Molecular Formula:C₁₆H₂₅N₃O₃S*ClH
Molecular Weight:375.92
Hs Code.:

Synonyms:(R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride

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Chemical Property of (R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride

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Technology Process of (R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride

There total 1 articles about (R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-44-5
phosgene

: 900174-67-6
(R)-tert-butyl 2-(5-amino-2-(isopropylsulfonyl)phenyl)pyrrolidine-1-carboxylate

: 506-59-2
N,N-dimethylammonium chloride

: 900176-10-5
(R)-3-(4-(Isopropylsulfonyl)-3-(pyrrolidin-2-yl)phenyl)-1,1-dimethylurea hydrochloride

Guidance literature:: phosgene; (R)-tert-butyl 2-(5-amino-2-(isopropylsulfonyl)phenyl)pyrrolidine-1-carboxylate; With sodium hydrogencarbonate; In dichloromethane; toluene; at 0 ℃; for 0.5h;

N,N-dimethylammonium chloride; With triethylamine; at 20 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 4h;