5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Base Information

Chemical Name:5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester
CAS No.:951784-64-8
Molecular Formula:C₁₇H₁₅N₃O₂S
Molecular Weight:325.391
Hs Code.:

Synonyms:5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Suppliers and Price of 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

There total 3 articles about 5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 951784-63-7
4-(2-amino-pyrimidin-4-yl)-2-benzoyl-4-oxo-butyric acid ethyl ester

: 951784-64-8
5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

: 951784-65-9
5-(2-amino-pyrimidin-4-yl)-2-phenyl-furan-3-carboxylic acid ethyl ester

Guidance literature:: With Lawessons reagent; In toluene; for 4h; Inert atmosphere; Reflux;
DOI:10.1021/jm100504d

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 951784-64-8
5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2: Lawessons reagent / toluene / 4 h / Heating / reflux

With Lawessons reagent; sodium hydride; In tetrahydrofuran; toluene;

Reference yield:

: 106157-91-9
2-Amino-4-bromoacetylpyrimidine

: 951784-64-8
5-(2-amino-pyrimidin-4-yl)-2-phenyl-thiophene-3-carboxylicacid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / 0 - 20 °C

2: Lawessons reagent / toluene / 4 h / Heating / reflux

With Lawessons reagent; sodium hydride; In tetrahydrofuran; toluene;