(E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1618099-63-0
• Molecular Formula: C₂₁H₂₅BO₃
• Molecular Weight: 336.239
• Mol file: 1618099-63-0.mol

Synonyms:(E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 2 articles about (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

pinacol vinylboronate (75927-49-0) + 1-Allyl-3-benzyloxy-benzene → (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1618099-63-0)

Guidance literature:

With [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene][2-isopropoxy-5-(2,2,2-trifluoroacetamido)benzylidene]ruthenium(II) dichloride; In toluene; for 1h; stereoselective reaction; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201402192

Reference yield:

1-ethynyl-3-(phenylmethoxy)benzene (128133-59-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1618099-63-0)

Guidance literature:

In neat (no solvent); at 110 ℃; for 14h;

DOI:10.1002/anie.201710415

Reference yield: 56.0%

diazoacetic acid ethyl ester (623-73-4) + (E)-2-(3-(benzyloxy)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1618099-63-0) → ethyl (1R,2S,3S)-2-(3-(benzyloxy)phenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropane-1-carboxylate

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; (S,S)-2,2'-isopropylidenebis(4-phenyl-2-oxazoline); In dichloromethane; at 25 ℃; for 8h; stereoselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201710415

upstream raw materials:

pinacol vinylboronate

1-ethynyl-3-(phenylmethoxy)benzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Downstream raw materials:

1-((3-((E)-2-azidovinyl)phenoxy)methyl)benzene