4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Base Information

Chemical Name:4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid
CAS No.:1464154-82-2
Molecular Formula:C₂₀H₁₁FN₄O₂
Molecular Weight:358.331
Hs Code.:

Synonyms:4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Suppliers and Price of 4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

There total 3 articles about 4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120153-08-4
4-(dihydroxyboranyl)-2-fluorobenzoic acid

: 1082604-63-4
4-(6-chloroimidazo[1,2-b]pyridazin-3-yl)benzonitrile

: 1464154-82-2
4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate; In water; N,N-dimethyl-formamide; at 20 - 80 ℃; for 18h; Inert atmosphere;

Reference yield:

: 923595-49-7
6-chloro-3-iodo-imidazo[1,2-b]pyridazine

: 1464154-82-2
4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere

2: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; N,N-dimethyl-formamide / 18 h / 20 - 80 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; potassium carbonate; In water; N,N-dimethyl-formamide;

Reference yield:

: 126747-14-6
4-cyanophenylboronic acid

: 1464154-82-2
4-(3-(4-cyanophenyl)imidazo[1,2-b]pyridazin-6-yl)-2-fluorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; N,N-dimethyl-formamide / 18 h / 90 °C / Inert atmosphere

2: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / water; N,N-dimethyl-formamide / 18 h / 20 - 80 °C / Inert atmosphere

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; potassium carbonate; In water; N,N-dimethyl-formamide;