1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone

Base Information

Chemical Name:1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone
CAS No.:51037-56-0
Molecular Formula:C₂₂H₂₄FN₃O₃
Molecular Weight:397.449
Hs Code.:
DSSTox Substance ID:DTXSID40965321
Nikkaji Number:J69.248D
Mol file:51037-56-0.mol

Synonyms:BRN 0860382;1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone;2-Benzimidazolinone, 1-(1-(3-(p-fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-;1-(4-Fluorophenyl)-2-hydroxy-4-(4-(2-oxo-1-benzimidazolinyl)-1-piperidyl)-1-butanone;5-24-02-00377 (Beilstein Handbook Reference);51037-56-0;SCHEMBL11834391;DTXSID40965321;LS-33248;1-[1-[3-(p-Fluorobenzoyl)-3-hydroxypropyl]-4-piperidyl]-1H-benzimidazol-2(3H)-one;1-(4-Fluorophenyl)-2-hydroxy-4-[4-(2-hydroxy-1H-benzimidazol-1-yl)piperidin-1-yl]butan-1-one

Suppliers and Price of 1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone

Chemical Property:

Density:1.301g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:397.18016980
Heavy Atom Count:29
Complexity:588

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCC(C(=O)C4=CC=C(C=C4)F)O

Technology Process of 1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone

There total 3 articles about 1-(1-(3-(p-Fluorobenzoyl)-3-hydroxypropyl)-4-piperidyl)-2-benzimidazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51037-74-2
1-p-fluorobenzoyl-1-bromo-3-chloro-propane

: 51037-56-0
1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-oxo-1-benzimidazolinyl)-1-piperidyl>-1-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / methanol / 24 h / Ambient temperature

2: potassium iodide / toluene / 20 h / Heating

With potassium iodide; In methanol; toluene;

Reference yield:

: 3874-54-2,41167-07-1
4-(4-fluorophenyl)-4-oxo-n-butyl chloride

: 51037-56-0
1-(4-fluorophenyl)-2-hydroxy-4-<4-(2-oxo-1-benzimidazolinyl)-1-piperidyl>-1-butanone

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / bromine, CaCO₃ / CHCl₃ / 8 h / Ambient temperature

2: 81 percent / methanol / 24 h / Ambient temperature

3: potassium iodide / toluene / 20 h / Heating

With bromine; calcium carbonate; potassium iodide; In methanol; chloroform; toluene;