(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

Base Information

Chemical Name:(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester
CAS No.:175227-24-4
Molecular Formula:C₁₇H₂₆O₄
Molecular Weight:294.391
Hs Code.:

Synonyms:(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

Chemical Property:

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Technology Process of (R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

There total 4 articles about (R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-2,2-Dimethyl-3-((R)-1-methyl-3-trimethylsilanyloxy-propoxy)-3-phenyl-propionic acid ethyl ester

: 175227-24-4
(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; Yield given; Ambient temperature;
DOI:10.1246/bcsj.69.3639

Reference yield:

: 31469-16-6
1-ethoxy-1-((trimethylsilyl)oxy)-2-methylpropene

: 175227-24-4
(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: oxazaborolidinone / CH₂Cl₂ / 1 h / -20 °C

2: Bu₄NF / tetrahydrofuran / Ambient temperature

With oxazaborolidinone; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1246/bcsj.69.3639

Reference yield:

: 100-52-7
benzaldehyde

: 175227-24-4
(R)-3-((R)-3-Hydroxy-1-methyl-propoxy)-2,2-dimethyl-3-phenyl-propionic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: oxazaborolidinone / CH₂Cl₂ / 1 h / -20 °C

3: Bu₄NF / tetrahydrofuran / Ambient temperature

With oxazaborolidinone; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1246/bcsj.69.3639