1-methylcyclohexyl trifluoroethyl ether

Base Information

• Chemical Name: 1-methylcyclohexyl trifluoroethyl ether
• CAS No.: 80764-78-9
• Molecular Formula: C₉H₁₅F₃O
• Molecular Weight: 196.213
• Mol file: 80764-78-9.mol

Synonyms:1-methylcyclohexyl trifluoroethyl ether

Chemical Property of 1-methylcyclohexyl trifluoroethyl ether

Chemical Property:

Purity/Quality:

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Technology Process of 1-methylcyclohexyl trifluoroethyl ether

There total 4 articles about 1-methylcyclohexyl trifluoroethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2,2-trifluoroethanol (75-89-8) + rac-cis-3-methylcyclohexyl p-toluenesulfonate (37690-41-8) → 1-methylcyclohex-1-ene (591-49-1) + 3-methyl-1-cyclohexene (591-48-0) + 4-methylcyclohexene (591-47-9) + 1-methylcyclohexyl trifluoroethyl ether (80764-78-9) + trans-3-methylcyclohexyl trifluoroethyl ether (80764-82-5) + cis-3-methylcyclohexyl trifluoroethyl ether (80764-81-4)

Guidance literature:

With pyridine; at 90 ℃; for 0.5h; Product distribution; other fluorinated alcohols; hydride shift in cyclohexyl tosylate solvolysis;

DOI:10.1021/jo00348a036

Reference yield:

2,2,2-trifluoroethanol (75-89-8) + (1-methylcyclopentyl)methyl 2,2,2-trifluoroethanesulfonate (75621-13-5) → 1-methylcyclohex-1-ene (591-49-1) + 1-ethylcyclopentene (2146-38-5) + 1-methylcyclohexyl trifluoroethyl ether (80764-78-9) + 1-Ethyl-1-(2,2,2-trifluoro-ethoxy)-cyclopentane + methylenecyclohexane (1192-37-6)

Guidance literature:

With water; at 25 ℃; Product distribution; Rate constant; deuterium isotope effect;

DOI:10.1021/ja00392a031

Reference yield:

2,2,2-trifluoroethanol (75-89-8) + (1-methylcyclopentyl)methyl p-bromobenzenesulfonate (75621-12-4) → 1-methylcyclohex-1-ene (591-49-1) + 1-ethylcyclopentene (2146-38-5) + 1-methylcyclohexyl trifluoroethyl ether (80764-78-9) + 1-Ethyl-1-(2,2,2-trifluoro-ethoxy)-cyclopentane + methylenecyclohexane (1192-37-6)

Guidance literature:

With water; at 25 ℃; Product distribution; Rate constant; deuterium isotope effect;

DOI:10.1021/ja00392a031

upstream raw materials:

2,2,2-trifluoroethanol

1-bromo-1-methylcyclohexane

rac-cis-3-methylcyclohexyl p-toluenesulfonate

(1-methylcyclopentyl)methyl 2,2,2-trifluoroethanesulfonate