Pregna-4,11-diene-3,20-dione

Base Information Edit

Chemical Name:Pregna-4,11-diene-3,20-dione
CAS No.:2625-60-7
Molecular Formula:C₂₁H₂₈O₂
Molecular Weight:312.452
Hs Code.:
NSC Number:22020
UNII:YUL6GTR69Y
DSSTox Substance ID:DTXSID90180885
Nikkaji Number:J83.642G
Wikipedia:11-Dehydroprogesterone
Wikidata:Q27116323
ChEMBL ID:CHEMBL44282
Mol file:2625-60-7.mol

Synonyms:Pregna-4,11-diene-3,20-dione;11-Dehydroprogesterone;2625-60-7;UNII-YUL6GTR69Y;YUL6GTR69Y;CHEBI:34929;NSC-22020;(8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-1,2,6,7,8,9,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one;4-07-00-02457 (Beilstein Handbook Reference);NSC 22020;BRN 3219163;CHEMBL44282;4,11-pregnadiene-3,20-dione;DTXSID90180885;NSC22020;11,12-DIDEHYDROPROGESTERONE;Q27116323

Suppliers and Price of Pregna-4,11-diene-3,20-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of Pregna-4,11-diene-3,20-dione Edit

Chemical Property:

Vapor Pressure:2.43E-08mmHg at 25°C
Refractive Index:1.556
Boiling Point:451.5 °C at 760 mmHg
Flash Point:168.2 °C
PSA：34.14000
Density:1.1 g/cm³
LogP:4.49950
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:312.208930132
Heavy Atom Count:23
Complexity:628

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCC2C1(C=CC3C2CCC4=CC(=O)CCC34C)C
Isomeric SMILES:CC(=O)[C@H]1CC[C@@H]2[C@@]1(C=C[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

Technology Process of Pregna-4,11-diene-3,20-dione

There total 20 articles about Pregna-4,11-diene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1109-03-1
12α-(toluene-sulfonyl-(4)-oxy)-5β-pregnanedione-(3,20)

: 7726-95-6
bromine

: 64-19-7,77671-22-8
acetic acid

: 1096-39-5
5β-H-11-pregnene-3,20-dione

: 2625-60-7
delta11-Progesterone

Guidance literature:: beim Erhitzen des Reaktionsprodukts mit Collidin;
DOI:10.1002/hlca.19460290316

Reference yield:

: 80-75-1,22847-91-2
11-alpha-hydroxyprogesterone

: 17652-16-3
pregna-4,9⁽¹¹⁾-diene-3,20-dione

: 2625-60-7
delta11-Progesterone

Guidance literature:: With pyridine; N-Bromosuccinimide; sulfur dioxide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) 25 deg C, 1 h;