thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

Base Information

Chemical Name:thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester
CAS No.:866782-17-4
Molecular Formula:C₁₉H₂₀FNO₃S
Molecular Weight:361.437
Hs Code.:

Synonyms:thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

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Chemical Property of thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

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Technology Process of thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

There total 7 articles about thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₂₀FNO₄S

: 866782-17-4
thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

Guidance literature:: With caesium carbonate; tiolacetic acid; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 12h;

Reference yield:

: C₁₈H₂₀FNO₅S

: 507-09-5
tiolacetic acid

: 866782-17-4
thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 866782-16-3
[(R)-2-(2-fluoro-phenyl)-1-hydroxymethyl-ethyl]-carbamic acid benzyl ester

: 866782-17-4
thioacetic acid S-[(R)-2-benzyloxycarbonylamino-3-(2-fluoro-phenyl)-propyl]ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 1 h / 0 °C

2: caesium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

With caesium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;