2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Base Information

Chemical Name:2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine
CAS No.:148692-02-8
Molecular Formula:C₃₃H₅₀N₅O₈PSi
Molecular Weight:703.848
Hs Code.:

Synonyms:2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Suppliers and Price of 2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

There total 3 articles about 2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 18395-90-9
Di-tert-butyldichlorosilane

: 148692-02-8
2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / AgNO₃ / dimethylformamide / 0.25 h / Ambient temperature

2: 1.) tetrazole, 2.) mCPBA / 1.) CH₂Cl₂, 3 h, 2.) 0 deg C, 1 h

With 1H-tetrazole; silver nitrate; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jo00063a055

Reference yield:

: 4546-55-8
N-benzoyladenosine

: 148692-02-8
2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / AgNO₃ / dimethylformamide / 0.25 h / Ambient temperature

2: 1.) tetrazole, 2.) mCPBA / 1.) CH₂Cl₂, 3 h, 2.) 0 deg C, 1 h

With 1H-tetrazole; silver nitrate; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl-formamide;
DOI:10.1021/jo00063a055

Reference yield:

: 117924-33-1
di-tert-butyl N,N-diethylphosphoramidite

: 148692-01-7
N⁶-benzoyl-3’,5’-O-di-tert-butylsilyl adenosine

: 148692-02-8
2'-O-(di-tert-butoxyphosphoryl)-3',5'-O-(di-tert-butylsilanediyl)-6-N-benzoyladenosine

Guidance literature:: With 1H-tetrazole; 3-chloro-benzenecarboperoxoic acid; Yield given. Multistep reaction; 1.) CH₂Cl₂, 3 h, 2.) 0 deg C, 1 h;
DOI:10.1021/jo00063a055