C₁₈H₂₀ClNO

Base Information

• Chemical Name: C₁₈H₂₀ClNO
• CAS No.: 540755-13-3
• Molecular Formula: C₁₈H₂₀ClNO
• Molecular Weight: 301.816
• Mol file: 540755-13-3.mol

Synonyms:C₁₈H₂₀ClNO

Chemical Property of C₁₈H₂₀ClNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₈H₂₀ClNO

There total 1 articles about C₁₈H₂₀ClNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Chlorobutanoyl chloride (4635-59-0) + dibenzylamine (103-49-1) → C18H20ClNO (540755-13-3)

Guidance literature:

chemoselective reaction;

DOI:10.1016/j.tetlet.2011.01.088

Reference yield: 96.0%

C18H20ClNO (540755-13-3) → 4-azido-N,N-dibenzylbutyramide (1286232-16-3)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 0.25h; Microwave irradiation;

DOI:10.1016/j.tetlet.2011.01.088

Reference yield:

C18H20ClNO (540755-13-3) → N1,N4-dibenzyl-1,4-diaminobutane (29867-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 0.25 h / 60 °C / Microwave irradiation

2: diborane / tetrahydrofuran / Inert atmosphere; Reflux

With sodium azide; diborane; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2011.01.088

upstream raw materials:

4-Chlorobutanoyl chloride

dibenzylamine

Downstream raw materials:

4-azido-N,N-dibenzylbutyramide

N₁,N₄-dibenzyl-1,4-diaminobutane