3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea

Base Information Edit

Chemical Name:3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea
CAS No.:79881-89-3
Molecular Formula:C13H18 N2 O3
Molecular Weight:250.298
Hs Code.:
European Community (EC) Number:411-970-3
DSSTox Substance ID:DTXSID30229944
Wikidata:Q83110321
Mol file:79881-89-3.mol

Synonyms:3-(3-acetyl-4-hydroxyphenyl)-1,1-diethylurea;A 1354;A-1354

Suppliers and Price of 3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 10 raw suppliers

Chemical Property of 3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea Edit

Chemical Property:

Vapor Pressure:9.8E-09mmHg at 25°C
Melting Point:142-143℃ (acetone )
Boiling Point:450.6°C at 760 mmHg
Flash Point:226.3°C
PSA：73.13000
Density:1.196g/cm³
LogP:2.48210
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:250.13174244
Heavy Atom Count:18
Complexity:303

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-48/22
Safety Statements: 22-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)NC1=CC(=C(C=C1)O)C(=O)C

Technology Process of 3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea

There total 7 articles about 3-(3-Acetyl-4-hydroxyphenyl)-1,1-diethylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.4%

: 1461-82-1
3-(4-Ethoxy-phenyl)-1,1-diethylharnstoff

: 75-36-5
acetyl chloride

: 79881-89-3
3-(3-Acetyl-4-hydroxy-phenyl)-1,1-diethylharnstoff

Guidance literature:: With aluminium trichloride; In nitrobenzene; at 25 - 30 ℃; for 4.5h;

Reference yield: 84.7%

: 1357457-94-3
4-(3,3-diethylureido)phenyl acetate

: 79881-89-3
3-(3-Acetyl-4-hydroxy-phenyl)-1,1-diethylharnstoff

Guidance literature:: With aluminum (III) chloride; sodium chloride; at 140 ℃; for 3h; Reagent/catalyst;
DOI:10.3184/174751911X13192995267028

Reference yield:

: 88-10-8
N,N-diethylcarbamyl chloride

: 79881-89-3
3-(3-Acetyl-4-hydroxy-phenyl)-1,1-diethylharnstoff

Guidance literature:: Multi-step reaction with 2 steps

1: 91.6 percent / KHCO₃ / acetone / 48 h / 20 - 30 °C

2: 93.4 percent / AlCl₃ / nitrobenzene / 4.5 h / 25 - 30 °C

With aluminium trichloride; potassium hydrogencarbonate; In nitrobenzene; acetone;