7-Nitrobenzoxadiazole-6-aminohexanoic acid

Base Information

Chemical Name:7-Nitrobenzoxadiazole-6-aminohexanoic acid
CAS No.:88235-25-0
Molecular Formula:C12H14N4O5
Molecular Weight:294.267
Hs Code.:2934999090
European Community (EC) Number:635-833-4
DSSTox Substance ID:DTXSID20236920
Nikkaji Number:J535.346G
Wikidata:Q27123278
Metabolomics Workbench ID:58136
Mol file:88235-25-0.mol

Synonyms:7-nitrobenzoxadiazole-6-aminohexanoic acid;N(7-nitro-2,1,3-benzoxadiazol-4-yl)-6-aminocaproic acid;N-(7-nitro-2,1,3-benzoxadiazol-4-yl)-6-aminohexanoic acid;NBD-AMHA

Suppliers and Price of 7-Nitrobenzoxadiazole-6-aminohexanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
NBDHexanoicAcid
1g
$ 1355.00

Sigma-Aldrich
6-(7-Nitrobenzofurazan-4-ylamino)hexanoic acid suitable for fluorescence
100mg
$ 180.00

Matrix Scientific
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid 95+%
250mg
$ 756.00

Matrix Scientific
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid 95+%
1g
$ 1647.00

Crysdot
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoicacid 95+%
1g
$ 780.00

Chemenu
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoicacid 95%
1g
$ 729.00

Cayman Chemical
C-6 NBD ≥96%
200mg
$ 155.00

Cayman Chemical
C-6 NBD ≥96%
1g
$ 504.00

American Custom Chemicals Corporation
6-(7-NITROBENZOFURAZAN-4-YLAMINO)- HEXANOIC ACID 95.00%
1G
$ 1871.10

American Custom Chemicals Corporation
6-(7-NITROBENZOFURAZAN-4-YLAMINO)- HEXANOIC ACID 95.00%
100MG
$ 739.20

Total 14 raw suppliers

Chemical Property of 7-Nitrobenzoxadiazole-6-aminohexanoic acid

Chemical Property:

Vapor Pressure:2.38E-13mmHg at 25°C
Refractive Index:1.65
Boiling Point:559.4 °C at 760 mmHg
PKA:4.74±0.10(Predicted)
Flash Point:292.1 °C
PSA：134.07000
Density:1.462 g/cm³
LogP:2.78410
Storage Temp.:2-8°C(protect from light)
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:294.09641956
Heavy Atom Count:21
Complexity:375

Purity/Quality:

97% ^*data from raw suppliers

NBDHexanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 23/24/25-36/37/38
Safety Statements: 22-26-36-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C(C2=NON=C2C(=C1)[N+](=O)[O-])NCCCCCC(=O)O
Uses 6-(7-NITRO-2,1,3-BENZOXADIAZOL-4-YLAMINO)HEXANOIC ACID is used for investigation of binding sites of fatty acid and sterol carrier proteins, also used for cell membrane staining. 6-(7-NITRO-2,1,3-BENZOXADIAZOL-4-YLAMINO)HEXANOIC ACID is used as a fluorescent probes for studying the fat globule (membrane) of bovine and human. NBD Hexanoic Acid is used as a fluorescent probes for studying the fat globule (membrane) of bovine and human.

Technology Process of 7-Nitrobenzoxadiazole-6-aminohexanoic acid

There total 6 articles about 7-Nitrobenzoxadiazole-6-aminohexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 10199-89-0
NBD chloride

: 60-32-2,93208-38-9
6-aminohexanoic acid

: 88235-25-0
6-(7-nitrobenzofurazan-4-ylamino)hexanoic acid

Guidance literature:: With sodium hydrogencarbonate; In methanol; at 0 - 50 ℃; for 3.5h;
DOI:10.1055/s-0034-1378537

Reference yield: 89.0%

: tert-butyl 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoate

: 88235-25-0
6-(7-nitrobenzofurazan-4-ylamino)hexanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 - 25 ℃; for 2h; Inert atmosphere;
DOI:10.1002/anie.202109967

Reference yield:

: 10199-89-0
NBD chloride

: 88235-25-0
6-(7-nitrobenzofurazan-4-ylamino)hexanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 940 mg / NaHCO₃ / methanol / 24 h

2: 325 mg / NaOH / H₂O; tetrahydrofuran / 3 h / 20 °C

With sodium hydroxide; sodium hydrogencarbonate; In tetrahydrofuran; methanol; water;
DOI:10.1021/ol0501931