N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

Base Information

Chemical Name:N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide
CAS No.:1623774-86-6
Molecular Formula:C₂₄H₃₀N₄O
Molecular Weight:390.528
Hs Code.:

Synonyms:N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

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Chemical Property of N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

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Technology Process of N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

There total 4 articles about N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 857772-05-5
C₁₂H₁₅ClO

: 1310826-33-5
2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-amine

: 1623774-86-6
N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

Guidance literature:: With triethylamine; In dichloromethane; Inert atmosphere; Schlenk technique;
DOI:10.1002/anie.201311024

Reference yield:

: 622-79-7
benzyl azide

: 1623774-86-6
N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / tert-butyl alcohol; water / 24 h / 20 °C / Inert atmosphere; Schlenk technique

2: triethylamine / dichloromethane / Inert atmosphere; Schlenk technique

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethylamine; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1002/anie.201311024

Reference yield:

: 2978-58-7
1,1-dimethylprop-3-ynylamine

: 1623774-86-6
N-(2-(1-benzyl-1H-1,2,3-triazol-4-yl)propan-2-yl)-2,2-dimethyl-3-(p-tolyl)propanamide

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / tert-butyl alcohol; water / 24 h / 20 °C / Inert atmosphere; Schlenk technique

2: triethylamine / dichloromethane / Inert atmosphere; Schlenk technique

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; triethylamine; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1002/anie.201311024