N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine

Base Information

• Chemical Name: N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine
• CAS No.: 1450982-30-5
• Molecular Formula: C₃₀H₂₈Br₂ClN₉
• Molecular Weight: 709.874
• Mol file: 1450982-30-5.mol

Synonyms:N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine

Chemical Property of N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine

There total 3 articles about N²,N⁴-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

N2,N4-bis(4-bromophenyl)-6-chloro-1,3,5-triazine-2,4-diamine (62785-05-1) + 7-chloro-N-(2-(piperazin-1-yl)ethyl)quinolin-4-amine (199444-71-8) → N2,N4-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine (1450982-30-5)

Guidance literature:

With potassium carbonate; In 1,4-dioxane; at 120 - 130 ℃;

DOI:10.1039/c3nj00317e

Reference yield:

aminoethylpiperazine (140-31-8) → N2,N4-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine (1450982-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 80 - 130 °C

2: potassium carbonate / 1,4-dioxane / 120 - 130 °C

With potassium carbonate; In 1,4-dioxane;

DOI:10.1039/c3nj00317e

Reference yield:

4,7-dichloroquinoline (86-98-6,1138471-54-1) → N2,N4-bis(4-bromophenyl)-6-(4-(2-((7-chloroquinolin-4-yl)amino)-ethyl)piperazin-1-yl)-1,3,5-triazine-2,4-diamine (1450982-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 h / 80 - 130 °C

2: potassium carbonate / 1,4-dioxane / 120 - 130 °C

With potassium carbonate; In 1,4-dioxane;

DOI:10.1039/c3nj00317e

upstream raw materials:

4,7-dichloroquinoline

N²,N⁴-bis(4-bromophenyl)-6-chloro-1,3,5-triazine-2,4-diamine

7-chloro-N-(2-(piperazin-1-yl)ethyl)quinolin-4-amine

aminoethylpiperazine