3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid

Base Information

• Chemical Name: 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid
• CAS No.: 63061-23-4
• Molecular Formula: C₁₄H₁₅NO₅
• Molecular Weight: 277.277
• Mol file: 63061-23-4.mol

Synonyms:3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid

Chemical Property of 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid

There total 3 articles about 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

maleic anhydride (108-31-6) + ethyl (4-amino-3,5-dibromophenyl)acetate (5438-70-0) → 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid (63061-23-4)

Guidance literature:

In diethyl ether; for 2h;

DOI:10.1007/s11178-006-0014-z

Reference yield:

→ (E)-3-(4-Ethoxycarbonylmethyl-phenylcarbamoyl)-acrylic acid (63061-23-4)

Guidance literature:

Maleinsaeureanhydrid, 4-NH2-Ph-CH2CO2Et;

Reference yield:

→ 3-[(4-ethoxycarbonylmethyl)phenylcarbamoyl]-2-propenoic acid (63061-23-4)

Guidance literature:

Maleinanhydrid, entspr. Anilin;

upstream raw materials:

maleic anhydride

ethyl (4-amino-3,5-dibromophenyl)acetate

Downstream raw materials:

ethyl [4-(2,5-dioxo-2,5-dihydro-1H-pyrrolyl)phenyl]acetate