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NOC-18

Base Information
  • Chemical Name:NOC-18
  • CAS No.:146724-94-9
  • Molecular Formula:C4H13N5O2
  • Molecular Weight:163.18
  • Hs Code.:29270000
  • Mol file:146724-94-9.mol
NOC-18

Synonyms:Ethanamine,2,2'-(hydroxynitrosohydrazono)bis- (9CI);DETA NONOate;DETA/NO;DiethylamineNONOate;Diethylamine diazeniumdiolate;NOC 18;

Suppliers and Price of NOC-18
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Sigma-Aldrich
  • NOC-18
  • 10mg
  • $ 173.90
  • Sigma-Aldrich
  • Diethylenetriamine/nitric oxide adduct ≥97% (NMR), solid
  • 50mg
  • $ 144.00
  • Sigma-Aldrich
  • 3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene ≥95%
  • 50mg
  • $ 954.00
  • Sigma-Aldrich
  • 3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene ≥95%
  • 10mg
  • $ 240.00
  • Sigma-Aldrich
  • Diethylenetriamine/nitric oxide adduct ≥97% (NMR), solid
  • 10mg
  • $ 231.00
  • ChemScene
  • NOC-18 ≥98.0%
  • 50mg
  • $ 420.00
  • ChemScene
  • NOC-18 ≥98.0%
  • 10mg
  • $ 120.00
  • Cayman Chemical
  • DETA NONOate ≥98%
  • 50mg
  • $ 94.00
  • Cayman Chemical
  • DETA NONOate ≥98%
  • 10mg
  • $ 29.00
  • Cayman Chemical
  • DETA NONOate ≥98%
  • 100mg
  • $ 174.00
Total 17 raw suppliers
Chemical Property of NOC-18
Chemical Property:
  • Appearance/Colour:White powder 
  • Vapor Pressure:9.2E-05mmHg at 25°C 
  • Melting Point:98-106 °C 
  • Refractive Index:1.8000 (estimate) 
  • Boiling Point:303.023 °C at 760 mmHg 
  • PKA:4.50±0.69(Predicted) 
  • Flash Point:137.064 °C 
  • PSA:108.18000 
  • Density:1.466 g/cm3 
  • LogP:-0.10600 
  • Storage Temp.:−20°C 
  • Solubility.:H2O: >20 mg/mL 
Purity/Quality:

98%,99%, *data from raw suppliers

NOC-18 *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Description DETA NONOate (146724-94-9) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of DETA NONOate in 0.1 M phosphate buffer at pH 7.4 is 20 hours at 37°C, or 56 hours at room temperature.1?Dissociation is essentially instantaneous at a pH of 5.0.
  • Uses A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37?C for 0.1mM NOC 5 is 21 hours. Other applications include the induction of dose dependent apoptosis in macrophages, and inhibition of lipoprotein oxidation induced by Cu2+ in vitro. 3,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazene has been used as a nitric oxide donor supplement for neuronal culture. It has also been used as a nitric oxide donor to study the effects of protein S-nitrosation (SNO) after nitrite treatment.
Technology Process of NOC-18

There total 1 articles about NOC-18 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With nitrogen(II) oxide; sodium methylate; In methanol; for 72h; under 3040.2 Torr;
DOI:10.1021/ol902282y
Guidance literature:
With perchloric acid; In water; at 25 ℃; pH=< 2; pH-value; Kinetics;
DOI:10.1016/j.jinorgbio.2014.08.008
upstream raw materials:

3-azapentane-1,5-diamine

Downstream raw materials:

nitrogen(II) oxide

3-azapentane-1,5-diamine

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