N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine

Base Information

• Chemical Name: N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine
• CAS No.: 326820-68-2
• Molecular Formula: C₅₀H₇₄N₄O₈S₄
• Molecular Weight: 987.424
• Mol file: 326820-68-2.mol

Synonyms:N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine

Chemical Property of N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine

There total 3 articles about N¹,N¹²-diethyl-N¹,N⁴,N⁹,N¹²-tetrakis(mesitylenesulfonyl)spermine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

ethyl iodide (75-03-6) + N1,N4,N9,N12-tetrakis(mesityenesulfonyl)spermine (326820-67-1) → N1,N12-diethyl-N1,N4,N9,N12-tetrakis(mesitylenesulfonyl)spermine (326820-68-2)

Guidance literature:

N¹,N⁴,N⁹,N¹²-tetrakis(mesityenesulfonyl)spermine; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

ethyl iodide; In N,N-dimethyl-formamide; at 20 ℃; Further stages.;

DOI:10.1021/jm000277+

Reference yield:

2-mesitylenesulphonyl chloride (773-64-8) → N1,N12-diethyl-N1,N4,N9,N12-tetrakis(mesitylenesulfonyl)spermine (326820-68-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 90 percent / aq. NaOH / CH₂Cl₂ / 20 °C

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: 93 percent / dimethylformamide / 20 °C

With sodium hydroxide; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm000277+

Reference yield:

spermine tetrahydrochloride (306-67-2) → N1,N12-diethyl-N1,N4,N9,N12-tetrakis(mesitylenesulfonyl)spermine (326820-68-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 90 percent / aq. NaOH / CH₂Cl₂ / 20 °C

2.1: NaH / dimethylformamide / 0.5 h / 20 °C

2.2: 93 percent / dimethylformamide / 20 °C

With sodium hydroxide; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm000277+

upstream raw materials:

ethyl iodide

N¹,N⁴,N⁹,N¹²-tetrakis(mesityenesulfonyl)spermine

2-mesitylenesulphonyl chloride

spermine tetrahydrochloride

Downstream raw materials:

N₁,N₁₂-diethylspermine