4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)

Base Information

• Chemical Name: 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)
• CAS No.: 253600-70-3
• Molecular Formula: C₄₁H₅₁BrO₂
• Molecular Weight: 655.759
• Mol file: 253600-70-3.mol

Synonyms:4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)

Chemical Property of 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)

There total 3 articles about 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanesulfonic acid 2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester (253600-68-9) → 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene) (253600-70-3)

Guidance literature:

With lithium bromide; In acetone; at 70 ℃; for 3h;

DOI:10.1002/(SICI)1521-3765(19991105)5:11<3310::AID-CHEM3310>3.0.CO;2-R

Reference yield:

4-[tris-(4-tert-butylphenyl)methyl]phenol (143998-20-3) → 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene) (253600-70-3)

Guidance literature:

Multi-step reaction with 4 steps

1: K₂CO₃ / dimethylformamide / 17 h / 60 °C

2: 82 percent / H₂O; HCl / CHCl₃; methanol / 18 h / Heating

3: 84 percent / NEt₃ / CH₂Cl₂ / 3 h / -5 °C

4: LiBr / acetone / 3 h / 70 °C

With hydrogenchloride; water; potassium carbonate; triethylamine; lithium bromide; In methanol; dichloromethane; chloroform; N,N-dimethyl-formamide; acetone; 1: Etherification / 2: Hydrolysis / 3: Mesylation / 4: Substitution;

DOI:10.1002/(SICI)1521-3765(19991105)5:11<3310::AID-CHEM3310>3.0.CO;2-R

Reference yield:

2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran (253600-67-8) → 4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene) (253600-70-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / H₂O; HCl / CHCl₃; methanol / 18 h / Heating

2: 84 percent / NEt₃ / CH₂Cl₂ / 3 h / -5 °C

3: LiBr / acetone / 3 h / 70 °C

With hydrogenchloride; water; triethylamine; lithium bromide; In methanol; dichloromethane; chloroform; acetone; 1: Hydrolysis / 2: Mesylation / 3: Substitution;

DOI:10.1002/(SICI)1521-3765(19991105)5:11<3310::AID-CHEM3310>3.0.CO;2-R

upstream raw materials:

methanesulfonic acid 2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

4-[tris-(4-tert-butylphenyl)methyl]phenol

2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran

Downstream raw materials:

C₄₃H₅₄O₃S

C₄₁H₅₂O₂S

5-[4-(5-{2-[2-(2,6-diisopropyl-phenoxy)-ethoxy]-ethoxy}-naphthalen-1-ylethynyl)-phenyl]-2-{4-[2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethylsulfanyl]-[1,3]dithiol-2-ylidene}-5H-[1,3]dithiolo[4,5-c]pyrrole

5-(4-iodo-phenyl)-2-{4-[2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethylsulfanyl]-[1,3]dithiol-2-ylidene}-5H-[1,3]dithiolo[4,5-c]pyrrole