2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran

Base Information

• Chemical Name: 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran
• CAS No.: 253600-67-8
• Molecular Formula: C₄₆H₆₀O₄
• Molecular Weight: 676.98
• Mol file: 253600-67-8.mol

Synonyms:2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran

Chemical Property of 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran

There total 11 articles about 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2'-iodoethoxy)ethyl-2-tetrahydropyranyl ether (88454-93-7) + 4-[tris-(4-tert-butylphenyl)methyl]phenol (143998-20-3) → 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran (253600-67-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 17h;

DOI:10.1002/(SICI)1521-3765(19991105)5:11<3310::AID-CHEM3310>3.0.CO;2-R

Reference yield:

tert-butylbenzene (253185-03-4,253185-04-5) → 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran (253600-67-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 6 percent

2: 97 percent / 20 h / 100 °C

3: 8.30 g / KOH / butan-1-ol; H₂O / 36 h / Heating

With potassium hydroxide; In water; butan-1-ol;

DOI:10.1021/jo00066a030

Reference yield:

1-bromo-4-tert-butylbenzene (3972-65-4) → 2-[2-(2-{4-[Tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-tetrahydro-pyran (253600-67-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) Mg / 1) THF, 2 h, 2) THF, reflux, overnight

2: 94 percent / acetyl chloride / 48 h / Heating

3: 97 percent / 20 h / 100 °C

4: 8.30 g / KOH / butan-1-ol; H₂O / 36 h / Heating

With potassium hydroxide; magnesium; acetyl chloride; In water; butan-1-ol;

DOI:10.1021/jo00066a030

upstream raw materials:

2-(2-(2-chloroethoxy)ethoxy)tetrahydro-2H-pyran

4-[tris-(4-tert-butylphenyl)methyl]phenol

2-(2'-iodoethoxy)ethyl-2-tetrahydropyranyl ether

3,4-dihydro-2H-pyran

Downstream raw materials:

4-(9-{4-[2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-phenyl}-[1,10]phenanthrolin-2-yl)-phenol

methanesulfonic acid 2-(2-{4-[tris-(4-tert-butyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

4,4',4''-((4-(2-(2-bromoethoxy)ethoxy)phenyl)methanetriyl)-tris(tert-butylbenzene)

mono-p-phenyl ether of di(ethylene glycol)