2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile

Base Information

Chemical Name:2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile
CAS No.:13312-85-1
Molecular Formula:C₈H₇NO₂
Molecular Weight:149.149
Hs Code.:
European Community (EC) Number:883-338-9
Nikkaji Number:J1.581.327J

Synonyms:SCHEMBL639888;2-hydroxy-2-(2-hydroxyphenyl)acetonitrile;EN300-6808985;13312-85-1

Suppliers and Price of 2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:149.047678466
Heavy Atom Count:11
Complexity:172

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(C#N)O)O

Technology Process of 2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile

There total 8 articles about 2-Hydroxy-2-(2-hydroxyphenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 151-50-8
potassium cyanide

: 90-02-8
salicylaldehyde

: 13312-85-1
2-hydroxy-2-(2-hydroxyphenyl)acetonitrile

Guidance literature:: In water; acetic acid; for 1h; Ambient temperature;

Reference yield: 10.0%

: 28752-82-1
2-(allyloxy)benzaldehyde

: 5804-85-3
diethylaluminium cyanide

: C₁₁H₁₁NO₂

: 13312-85-1
2-hydroxy-2-(2-hydroxyphenyl)acetonitrile

: 90-02-8
salicylaldehyde

: 2-hydroxy-2-(2-allyloxyphenyl)acetonitrile

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; tricyclohexylphosphine; In toluene; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1039/b918626c

Reference yield:

: 613-90-1
benzoyl cyanide

: 90-02-8
salicylaldehyde

: 13312-85-1
2-hydroxy-2-(2-hydroxyphenyl)acetonitrile

: 74552-60-6
2-Hydroxy-2-(2-hydroxyphenyl)-1-phenylethanone

: 134-81-6
benzil

Guidance literature:: With titanium(III) chloride; acetic acid; Yield given. Multistep reaction. Yields of byproduct given; 1) water, 2 h, r.t., 2) CHCl₃, 1 week;
DOI:10.1021/jo00062a038