C₂₀H₂₅NO

Base Information

• Chemical Name: C₂₀H₂₅NO
• CAS No.: 1017592-99-2
• Molecular Formula: C₂₀H₂₅NO
• Molecular Weight: 295.425
• Mol file: 1017592-99-2.mol

Synonyms:C₂₀H₂₅NO

Chemical Property of C₂₀H₂₅NO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₅NO

There total 4 articles about C₂₀H₂₅NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H27NO → C20H25NO (1017592-99-2)

Guidance literature:

C₂₀H₂₇NO; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.5h;

With triethylamine; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1002/ejoc.201800631

Reference yield:

benzyl bromide (100-39-0) → C20H25NO (1017592-99-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / water / 24 h / 80 °C

2.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C

3.2: Swern Oxidation / 0.5 h / 20 °C

With lithium aluminium tetrahydride; oxalyl dichloride; potassium carbonate; dimethyl sulfoxide; In diethyl ether; dichloromethane; water; 3.1: |Swern Oxidation;

DOI:10.1002/ejoc.201800631

Reference yield:

L-isoleucine (73-32-5,959215-79-3,18875-42-8) → C20H25NO (1017592-99-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium carbonate / water / 24 h / 80 °C

2.1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C

3.2: Swern Oxidation / 0.5 h / 20 °C

With lithium aluminium tetrahydride; oxalyl dichloride; potassium carbonate; dimethyl sulfoxide; In diethyl ether; dichloromethane; water; 3.1: |Swern Oxidation;

DOI:10.1002/ejoc.201800631

upstream raw materials:

benzyl bromide

L-isoleucine

Downstream raw materials:

C₂₇H₃₁F₂NO₃S