methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

Base Information

Chemical Name:methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate
CAS No.:1257387-87-3
Molecular Formula:C₂₆H₃₂F₂N₂O₃
Molecular Weight:458.548
Hs Code.:

Synonyms:methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

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Technology Process of methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

There total 4 articles about methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 1257388-03-6
2-bromo-1-(3,5-difluoro-phenyl)-ethanone-oxime

: 1257387-86-2
methyl (S)-2-benzylamino-3-cycloheptyl-propionate

: 1257387-87-3
methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 863972-47-8
methyl (2S)-2-amino-3-cycloheptylpropanoate

: 1257387-87-3
methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 3.5 h / 100 °C

2: potassium carbonate / tetrahydrofuran / 20 °C

With potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

Reference yield:

: 220607-75-0
2-bromo-1-(3,5-difluorophenyl)ethanone

: 1257387-87-3
methyl (S)-2-(benzyl-{2-(3,5-difluorophenyl)-2-[hydroxyimino]ethyl}amino)-3-cycloheptylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / methanol; water / 20 °C

2: potassium carbonate / tetrahydrofuran / 20 °C

With hydroxylamine hydrochloride; potassium carbonate; In tetrahydrofuran; methanol; water;