{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

Base Information

Chemical Name:{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester
CAS No.:1034776-25-4
Molecular Formula:C₂₁H₂₄N₂O₃
Molecular Weight:352.433
Hs Code.:

Synonyms:{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

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Chemical Property of {4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

Chemical Property:

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Technology Process of {4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

There total 1 articles about {4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1034776-13-0
{4-[(1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

: 1034776-25-4
{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

Guidance literature:: {4-[(1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester; With sodium cyanoborohydride; acetic acid; at 20 ℃; for 2.25h;

With sodium hydroxide; In water;

Reference yield: 51.0%

: 1034776-25-4
{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

: 88040-86-2
2-methoxy-5-methylbenzene sulfonyl chloride

: 1034776-27-6
4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

Guidance literature:: With pyridine; at 20 ℃; for 1h;

Reference yield:

: 1034776-25-4
{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

: 88040-86-2
2-methoxy-5-methylbenzene sulfonyl chloride

: 1034775-79-5
(4-{[1-(2-Methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1 h / 20 °C

2: hydrogenchloride / 1,4-dioxane / 18 h / 20 °C

With pyridine; hydrogenchloride; In 1,4-dioxane;