4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

Base Information

Chemical Name:4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester
CAS No.:1034776-27-6
Molecular Formula:C₂₉H₃₂N₂O₆S
Molecular Weight:536.649
Hs Code.:

Synonyms:4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

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Chemical Property of 4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

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Technology Process of 4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

There total 2 articles about 4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1034776-25-4
{4-[(2,3-dihydro-1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

: 88040-86-2
2-methoxy-5-methylbenzene sulfonyl chloride

: 1034776-27-6
4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

Guidance literature:: With pyridine; at 20 ℃; for 1h;

Reference yield:

: 1034776-13-0
{4-[(1H-indole-6-carbonyl)-amino]-phenyl}-acetic acid tert-butyl ester

: 1034776-27-6
4-{[1-(2-methoxy-5-methyl-benzenesulfonyl)-2,3-dihydro-1H-indole-6-carbonyl]-amino}-phenyl acetic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium cyanoborohydride; acetic acid / 2.25 h / 20 °C

2: pyridine / 1 h / 20 °C

With pyridine; sodium cyanoborohydride; acetic acid;