(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

Base Information

Chemical Name:(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide
CAS No.:349471-98-3
Molecular Formula:C₂₈H₄₈ClNO₅SSi
Molecular Weight:574.297
Hs Code.:

Synonyms:(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

Suppliers and Price of (+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

There total 1 articles about (+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 18303-04-3
N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide

: 244262-56-4
(Z)-6-Chloro-3-methyl-5-triisopropylsilanyloxy-hex-3-en-1-ol

: 349471-98-3
(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/S0040-4020(01)00290-3

Reference yield: 81.0%

: 349471-98-3
(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

: 349471-99-4
(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-tosylamide

Guidance literature:: In dimethyl sulfoxide; at 170 - 180 ℃; for 0.333333h;
DOI:10.1016/S0040-4020(01)00290-3

Reference yield:

: 349471-98-3
(+/-)-N-(6-chloro-3-methyl-5-triisopropylsiloxyhex-3-ene)-N-t-butoxycarbonyl-N-tosylamide

: 349472-00-0
(+/-)-(3Z,9E,11Z)-7-aza-1-chloro-4-methyl-12-(2-methoxycarbonyl-3-oxo)cyclopentyl-2-oxo-7-p-toluenesulfonyldodeca-3,9,11-triene

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / dimethylsulfoxide / 0.33 h / 170 - 180 °C

2: 95 percent / DIAD; PPh₃ / tetrahydrofuran / 3 h / 20 °C

3: 1.8 g / aq. TFA / CH₂Cl₂ / 0.75 h / 0 °C

4: 92 percent / TBAF / tetrahydrofuran / 5 h / -20 - 20 °C

5: 79 percent / Dess-Martin periodinane / CH₂Cl₂ / 2.5 h / 0 °C

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; Dess-Martin periodane; triphenylphosphine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; 2: Mitsunobu reaction / 5: Dess-Martin oxidation;
DOI:10.1016/S0040-4020(01)00290-3