C₄₅H₄₅NO₄

Base Information

• Chemical Name: C₄₅H₄₅NO₄
• CAS No.: 1026184-18-8
• Molecular Formula: C₄₅H₄₅NO₄
• Molecular Weight: 663.857
• Mol file: 1026184-18-8.mol

Synonyms:C₄₅H₄₅NO₄

Chemical Property of C₄₅H₄₅NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₅H₄₅NO₄

There total 8 articles about C₄₅H₄₅NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-3’,5’-dibenzyloxyphenylbromohydrin (103145-34-2) → C45H45NO4 (1026184-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / tetrahydrofuran; methanol / 2 h / 20 °C

2: 20 h / 120 °C

With potassium carbonate; In tetrahydrofuran; methanol;

DOI:10.1021/jm070030d

Reference yield:

1-(4-benzyloxyphenyl)-2-benzylaminopropane (65033-31-0) → C45H45NO4 (1026184-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 28 percent / (R)-(-)-mandelic acid / methanol / Heating

2: 20 h / 120 °C

With (R)-Mandelic Acid; In methanol;

DOI:10.1021/jm070030d

Reference yield:

2-bromo-1-[3,5-bis(phenylmethoxy)phenyl]ethanone (28924-18-7) → C45H45NO4 (1026184-18-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 78 percent / BH₃*Me₂S; (1R,2S)-(+)-cis-1-amino-2-indanol / diethyl ether; tetrahydrofuran / 2 h

2: K₂CO₃ / tetrahydrofuran; methanol / 2 h / 20 °C

3: 20 h / 120 °C

With dimethylsulfide borane complex; (1R,2S)-1-Amino-2-indanol; potassium carbonate; In tetrahydrofuran; methanol; diethyl ether;

DOI:10.1021/jm070030d

upstream raw materials:

(R)-(-)-1-(4-benzyloxyphenyl)-2-benzylaminopropane

(R)-2-(3,5-bis(benzyloxy)phenyl)oxirane

1-(4-benzyloxyphenyl)-2-benzylaminopropane

(R)-3’,5’-dibenzyloxyphenylbromohydrin

Downstream raw materials:

(R,R)-(-)-Fenoterol