methyl(2R^,3R^,4R^,5R^)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Base Information

Chemical Name:methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate
CAS No.:121485-05-0
Molecular Formula:C₁₅H₂₀O₅
Molecular Weight:280.321
Hs Code.:

methyl(2R<sup>*</sup>,3R<sup>*</sup>,4R<sup>*</sup>,5R<sup>*</sup>)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Synonyms:methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Suppliers and Price of methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

There total 3 articles about methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 137532-03-7,143729-24-2
(2R^*,3R^*,4R^*,5S^*)-6-benzyloxy-2-hydroxy-5-iodo-3-methyl-4-hexanolide

: 121485-05-0
methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Guidance literature:: With sodium carbonate; for 48h; Ambient temperature;
DOI:10.1246/bcsj.65.1841

Reference yield:

: 120506-06-1
isopropyl (2S,3R,4E)-6-benzyloxy-2-hydroxy-3-methyl-4-hexenoate

: 121485-05-0
(2S,3S)-3-((2S,3R)-3-Benzyloxymethyl-oxiranyl)-2-hydroxy-butyric acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / H₂O; methanol

2: 1.) I₂; 2.) Na₂CO₃ / 1.) CH₃CN, 0 deg C; 2.) r.t.

With potassium hydroxide; iodine; sodium carbonate; In methanol; water;
DOI:10.1016/S0040-4039(00)80738-8

Reference yield:

: 120506-06-1,120575-89-5,120575-90-8,120575-91-9,120575-92-0,121570-18-1,143729-26-4,143729-27-5,143729-28-6
isoprpyl (2R^*,3S^*,4E)-6-benzyloxy-2-hydroxy-3-methyl-4-hexenoate

: 121485-05-0
methyl(2R^*,3R^*,4R^*,5R^*)-6-benzyloxy-4,5-epoxy-2-hydroxy-3-methylhexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 1 M aq. KOH, 2.) iodine / 1.) methanol, RT, 1 d, 2.) acetonitrile, 0 deg C, 18 h

2: 90 percent / Na₂CO₃ / 48 h / Ambient temperature

With potassium hydroxide; iodine; sodium carbonate;
DOI:10.1246/bcsj.65.1841