(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Base Information

Chemical Name:(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate
CAS No.:1352151-74-6
Molecular Formula:C₂₀H₂₈IN₃O₄
Molecular Weight:501.365
Hs Code.:

Synonyms:(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Suppliers and Price of (S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

There total 3 articles about (S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103882-09-3,62129-44-6
N-Boc-4-I-Phe-OH

: 1352151-74-6
(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethylmorpholine; / N,N-dimethyl-formamide / 0.5 h / 20 °C

1.2: 16 h / 0 - 28 °C

2.1: trifluoroacetic acid / dichloromethane / 50 h

3.1: triethylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 24 h / 17 - 28 °C

With N-ethylmorpholine;; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 35264-09-6
1-(tert-butoxycarbonylamino)cyclopentanecarboxylic acid

: 97964-72-2
(S)-2-amino-3-(4-iodophenyl)propionamamide

: 1352151-74-6
(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In N,N-dimethyl-formamide; at 17 - 28 ℃; for 24h;

Reference yield:

: 868694-44-4
[(1S)-1-carbamoyl-2-(4-iodophenyl)ethyl]carbamic acid tert-butyl ester

: 1352151-74-6
(S)-tert-butyl 1-(1-amino-3-(4-iodophenyl)-1-oxopropan-2-ylcarbamoyl)cyclopentylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 50 h

2: triethylamine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / N,N-dimethyl-formamide / 24 h / 17 - 28 °C

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;