Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester
CAS No.:143218-20-6
Molecular Formula:C₂₄H₂₆N₂O₆
Molecular Weight:438.48
Hs Code.:
DSSTox Substance ID:DTXSID501111150

Synonyms:DTXSID501111150;143218-20-6;Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester

Suppliers and Price of Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:438.17908655
Heavy Atom Count:32
Complexity:670

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)C(=O)ON3C(=O)CCC3=O

Technology Process of Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester

There total 5 articles about Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-2,2-diphenylethyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 119363-63-2
2-(N-tert-butoxycarbonylamino)-3,3-diphenylpropanoic acid

: 143218-20-6
2-tert-Butoxycarbonylamino-3,3-diphenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane; for 4h;
DOI:10.1021/jm00096a010

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 143218-20-6
2-tert-Butoxycarbonylamino-3,3-diphenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

2: 94 percent / DCC / 1,2-dimethoxy-ethane / 4 h

With sodium hydroxide; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; water;
DOI:10.1021/jm00096a010

Reference yield:

: 143646-43-9
ethyl acetamido(diphenylmethyl)cyanoacetate

: 143218-20-6
2-tert-Butoxycarbonylamino-3,3-diphenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / 20percent aq. HCl / 30 h / Heating

2: 90 percent / NaOH / dioxane; H₂O / 2 h / Ambient temperature

3: 94 percent / DCC / 1,2-dimethoxy-ethane / 4 h

With hydrogenchloride; sodium hydroxide; dicyclohexyl-carbodiimide; In 1,4-dioxane; 1,2-dimethoxyethane; water;
DOI:10.1021/jm00096a010