N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine

Base Information

• Chemical Name: N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine
• CAS No.: 1263201-42-8
• Molecular Formula: C₂₉H₄₅N₃O₆S₂
• Molecular Weight: 595.825
• Mol file: 1263201-42-8.mol

Synonyms:N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine

Chemical Property of N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine

There total 1 articles about N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2-mesitylenesulphonyl chloride (773-64-8) + tert-butyl N-{3-[(3-aminopropyl)amino]propyl}carbamate (82409-04-9) → N1,N4-bis(mesitylenesulfonyl)-N7-(tert-butoxycarbonyl)norspermidine (1263201-42-8)

Guidance literature:

With sodium hydroxide; In dichloromethane; water; at 20 ℃; Cooling with ice; Inert atmosphere;

DOI:10.1055/s-0030-1258245

Reference yield: 70.0%

N1,N4-bis(mesitylenesulfonyl)-N7-(tert-butoxycarbonyl)norspermidine (1263201-42-8) + 4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester (108052-76-2) → N1,N4-bis(mesitylenesulfonyl)-N7-(tert-butoxycarbonyl)-N1-[4-(tert-butoxycarbonyl)benzyl]norspermidine (1263201-43-9)

Guidance literature:

N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)norspermidine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; Inert atmosphere;

4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester; In N,N-dimethyl-formamide; mineral oil; at 70 ℃; for 12.5h; Inert atmosphere;

DOI:10.1055/s-0030-1258245

upstream raw materials:

2-mesitylenesulphonyl chloride

tert-butyl N-{3-[(3-aminopropyl)amino]propyl}carbamate

Downstream raw materials:

N₁,N₄-bis(mesitylenesulfonyl)-N₇-(tert-butoxycarbonyl)-N₁-[4-(tert-butoxycarbonyl)benzyl]norspermidine