p-chlorophenyl heptanoate

Base Information

• Chemical Name: p-chlorophenyl heptanoate
• CAS No.: 85069-30-3
• Molecular Formula: C₁₃H₁₇ClO₂
• Molecular Weight: 240.73
• Mol file: 85069-30-3.mol

Synonyms:p-chlorophenyl heptanoate

Chemical Property of p-chlorophenyl heptanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of p-chlorophenyl heptanoate

There total 1 articles about p-chlorophenyl heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-phenol (106-48-9,82344-39-6) + Heptanoic acid chloride (2528-61-2) → p-chlorophenyl heptanoate (85069-30-3)

Guidance literature:

DOI:10.1021/ja01333a058

Reference yield: 76.0%

1-phenyl-3-butanol (2344-70-9) + p-chlorophenyl heptanoate (85069-30-3) → (R)-4-phenylbutan-2-yl heptanoate

Guidance literature:

With trimethylamine-N-oxide; Novozym 435 lipase; tetra(4-methoxyphenyl)cyclopentadienone iron tricarbonyl; In toluene; at 70 ℃; for 24h; enantioselective reaction; Inert atmosphere; Enzymatic reaction;

DOI:10.1016/j.tetlet.2017.05.038

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + p-chlorophenyl heptanoate (85069-30-3) → acetophenone (98-86-2) + Heptanoic acid (R)-1-phenyl-ethyl ester

Guidance literature:

With trimethylamine-N-oxide; Novozym 435 lipase; tetra(4-methoxyphenyl)cyclopentadienone iron tricarbonyl; In toluene; at 70 ℃; for 24h; enantioselective reaction; Inert atmosphere; Enzymatic reaction;

DOI:10.1016/j.tetlet.2017.05.038

upstream raw materials:

4-chloro-phenol

Heptanoic acid chloride

Downstream raw materials:

1-(5-chloro-2-hydroxy-phenyl)-heptan-1-one

acetophenone