Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester

Base Information

• Chemical Name: Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester
• CAS No.: 86767-91-1
• Molecular Formula: C₁₅H₁₉ClN₂OS₂
• Molecular Weight: 342.914
• Mol file: 86767-91-1.mol

Synonyms:Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester

Chemical Property of Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester

There total 3 articles about Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

Diethyldithiocarbamic acid (147-84-2) + 4-Chloro-N-(1-chloro-cyclopropyl)-benzamide (86767-79-5) → Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester (86767-91-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 1h;

DOI:10.1002/ardp.19833160705

Reference yield:

4-chloro-benzoyl chloride (122-01-0) → Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester (86767-91-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / Et₃N / tetrahydrofuran / 1 h

2: 72 percent / SOCl₂ / CHCl₃ / 1.) room temp., 30 min, 2.) 40 deg C, 5 min

3: 76 percent / Et₃N / tetrahydrofuran / 1 h

With thionyl chloride; triethylamine; In tetrahydrofuran; chloroform;

DOI:10.1002/ardp.19833160705

Reference yield:

4-Chloro-N-(1-hydroxy-cyclopropyl)-benzamide (86750-55-2) → Diethyl-dithiocarbamic acid 1-(4-chloro-benzoylamino)-cyclopropyl ester (86767-91-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / SOCl₂ / CHCl₃ / 1.) room temp., 30 min, 2.) 40 deg C, 5 min

2: 76 percent / Et₃N / tetrahydrofuran / 1 h

With thionyl chloride; triethylamine; In tetrahydrofuran; chloroform;

DOI:10.1002/ardp.19833160705

upstream raw materials:

Diethyldithiocarbamic acid

4-Chloro-N-(1-chloro-cyclopropyl)-benzamide

4-chloro-benzoyl chloride

4-Chloro-N-(1-hydroxy-cyclopropyl)-benzamide

Refernces