(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

Base Information

Chemical Name:(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol
CAS No.:172925-68-7
Molecular Formula:C₁₆H₁₂F₂O
Molecular Weight:258.267
Hs Code.:

Synonyms:(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

Suppliers and Price of (1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of (1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of (1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

There total 2 articles about (1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 167155-75-1
1,1-difluoro-1a,10b-dihydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-one

: 172925-68-7
(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

Guidance literature:: With sodium hydroxide; sodium tetrahydroborate; In ethyl acetate; at 20 - 25 ℃; for 3h;
DOI:10.1021/jo049051v

Reference yield:

: 2222-33-5
dibenzosuberenon

: 172925-68-7
(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]-cyclohepten-6-ol

Guidance literature:: Multi-step reaction with 2 steps

1: triethylene glycol dimethyl ether / 180 °C

2: 9.5 kg / NaBH₄; aq. NaOH / ethyl acetate / 3 h / 20 - 25 °C

With sodium hydroxide; sodium tetrahydroborate; In Triethylene glycol dimethyl ether; ethyl acetate;
DOI:10.1021/jo049051v