N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline

Base Information

• Chemical Name: N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline
• CAS No.: 138814-14-9
• Molecular Formula: C₂₆H₂₇N₃O₃S
• Molecular Weight: 461.585

Synonyms:N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline

Chemical Property of N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline

There total 13 articles about N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

6-(methylacetylamino)-7-nitro-N-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-1,2,3,4-tetrahydroquinoline (138814-26-3) + acetic acid (64-19-7,77671-22-8) → N1,2-dimethyl-N5-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline (138814-14-9)

Guidance literature:

With tin; Heating;

DOI:10.1021/jm00083a007

Reference yield:

6-aminoquinoline (580-15-4) → N1,2-dimethyl-N5-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline (138814-14-9)

Guidance literature:

Multi-step reaction with 6 steps

1: 77 percent / CH₂Cl₂ / 0.17 h / 25 °C

2: 85 percent / H₂ / PtO₂ / acetic acid / 1.5 h / 1551.4 Torr

3: 98percent H₂SO₄, 70percent HNO₃ / -10 °C

4: 82 percent / diisopropylethylamine / dimethylformamide / 5 h / 70 °C

5: 49 percent / K₂CO₃ / dimethylformamide / 48 h / 80 °C

6: 63 percent / Sn / Heating

With tin; sulfuric acid; hydrogen; nitric acid; potassium carbonate; N-ethyl-N,N-diisopropylamine; platinum(IV) oxide; In dichloromethane; acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/jm00083a007

Reference yield:

N-(Quinolin-6-yl)acetamide (22433-76-7) → N1,2-dimethyl-N5-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline (138814-14-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 85 percent / H₂ / PtO₂ / acetic acid / 1.5 h / 1551.4 Torr

2: 98percent H₂SO₄, 70percent HNO₃ / -10 °C

3: 82 percent / diisopropylethylamine / dimethylformamide / 5 h / 70 °C

4: 49 percent / K₂CO₃ / dimethylformamide / 48 h / 80 °C

5: 63 percent / Sn / Heating

With tin; sulfuric acid; hydrogen; nitric acid; potassium carbonate; N-ethyl-N,N-diisopropylamine; platinum(IV) oxide; In acetic acid; N,N-dimethyl-formamide;

DOI:10.1021/jm00083a007

upstream raw materials:

6-(methylacetylamino)-7-nitro-N-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-1,2,3,4-tetrahydroquinoline

acetic acid

bis(phenyl) carbonate

6-aminoquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 138814-14-9 N¹,2-dimethyl-N⁵-<4-<(4-methoxyphenyl)sulfonyl>benzyl>-5,6,7,8-tetrahydro-1H-imidazo<4,5-g>quinoline

Send

Send

Metric Ton KG G Pound L ML

Send

Send