(3-cyclohexenyl)-iodomethane

Base Information

• Chemical Name: (3-cyclohexenyl)-iodomethane
• CAS No.: 119867-11-7
• Molecular Formula: C₇H₁₁I
• Molecular Weight: 222.069
• Mol file: 119867-11-7.mol

Synonyms:(3-cyclohexenyl)-iodomethane

Chemical Property of (3-cyclohexenyl)-iodomethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (3-cyclohexenyl)-iodomethane

There total 2 articles about (3-cyclohexenyl)-iodomethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

cyclohex-3-enylmethanol (72581-32-9,1679-51-2) → (3-cyclohexenyl)-iodomethane (119867-11-7)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere; Cooling with ice;

DOI:10.1021/jacs.7b04312

Reference yield: 60.0%

cyclohex-3-en-1-ylmethyl 4-methylbenzenesulfonate (92864-78-3) → (3-cyclohexenyl)-iodomethane (119867-11-7)

Guidance literature:

With sodium iodide; In acetone; for 24h; Heating;

DOI:10.1016/S0040-4020(01)00817-1

Reference yield: 80.0%

(3-cyclohexenyl)-iodomethane (119867-11-7) + isobutyric Acid (79-31-2) → C11H18O2 (1352812-27-1)

Guidance literature:

isobutyric Acid; With lithium diisopropyl amide; In tetrahydrofuran; at 0 - 45 ℃;

(3-cyclohexenyl)-iodomethane; In tetrahydrofuran; at 20 - 45 ℃;

DOI:10.1002/chem.201102476

upstream raw materials:

cyclohex-3-en-1-ylmethyl 4-methylbenzenesulfonate

cyclohex-3-enylmethanol

Downstream raw materials:

diethyl 3-(3-cyclohexenyl)-2-methylpropanoate-2-carboxylate

ethyl 3-(3-cyclohexenyl)-2,2-dichloropropanoate

3-(3-cyclohexenyl)-propiophenone N,N-dimethylhydrazone

3-(cyclohex-3-en-1-yl)-1-phenyl-1-propanone

Refernces

• 1、 Rezazadeh, Sina,Devannah, Vijayarajan,Watson, Donald A.. "Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides". supporting information. p. 8110 - 8113. Retrieved 2017/06/28.