C₂₃H₂₃BrN₂O

Base Information

• Chemical Name: C₂₃H₂₃BrN₂O
• CAS No.: 1398592-35-2
• Molecular Formula: C₂₃H₂₃BrN₂O
• Molecular Weight: 423.352
• Mol file: 1398592-35-2.mol

Synonyms:C₂₃H₂₃BrN₂O

Chemical Property of C₂₃H₂₃BrN₂O

Chemical Property:

Purity/Quality:

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Technology Process of C₂₃H₂₃BrN₂O

There total 2 articles about C₂₃H₂₃BrN₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

C16H21N2O3P (1032761-06-0) + 4-(4-bromobutoxy)benzaldehyde (72621-19-3) → C23H23BrN2O (1398592-35-2)

Guidance literature:

With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at 0 - 20 ℃; for 3h;

DOI:10.1021/jo3016659

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → C23H23BrN2O (1398592-35-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 12 h / Reflux

2: potassium hexamethylsilazane / tetrahydrofuran; toluene / 3 h / 0 - 20 °C

With potassium hexamethylsilazane; potassium carbonate; In tetrahydrofuran; toluene; acetonitrile; 2: |Horner-Wadsworth-Emmons Olefination;

DOI:10.1021/jo3016659

Reference yield: 94.0%

C23H23BrN2O (1398592-35-2) → C23H23N5O (1398592-36-3)

Guidance literature:

With sodium azide; 18-crown-6 ether; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 55 ℃; for 12h;

DOI:10.1021/jo3016659

upstream raw materials:

C₁₆H₂₁N₂O₃P

4-(4-bromobutoxy)benzaldehyde

4-hydroxy-benzaldehyde

Downstream raw materials:

C₂₃H₂₃N₅O