Technology Process of (1S,2S)-trans-2-(4-phenoxybenzenesulfonamido)cyclopentyl thiobenzoate
There total 5 articles about (1S,2S)-trans-2-(4-phenoxybenzenesulfonamido)cyclopentyl thiobenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/jm400529f
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: Isopropenyl acetate; lipase Amano AK-20 / tert-butyl methyl ether / 72 h / 20 °C / Inert atmosphere; Enzymatic reaction
2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 20 °C / Inert atmosphere
3.1: lithium hydroxide; methanol / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
4.1: triphenylphosphine / tetrahydrofuran; water / 6 h / 20 - 65 °C
4.2: 3 h / 0 - 20 °C / Inert atmosphere
5.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 20 °C / Inert atmosphere
With
methanol; Isopropenyl acetate; lipase Amano AK-20; triphenylphosphine; lithium hydroxide; diethylazodicarboxylate;
In
tetrahydrofuran; tert-butyl methyl ether; water;
2.1: |Mitsunobu Displacement / 5.1: |Mitsunobu Displacement;
DOI:10.1021/jm400529f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triphenylphosphine / tetrahydrofuran; water / 6 h / 20 - 65 °C
1.2: 3 h / 0 - 20 °C / Inert atmosphere
2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 20 °C / Inert atmosphere
With
triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; water;
2.1: |Mitsunobu Displacement;
DOI:10.1021/jm400529f
