(S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

Base Information

Chemical Name:(S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine
CAS No.:1407513-02-3
Molecular Formula:C₂₆H₂₅BrN₂O₂
Molecular Weight:477.401
Hs Code.:

Synonyms:(S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

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Chemical Property of (S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

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Technology Process of (S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

There total 1 articles about (S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 1189178-87-7
6-bromo-3-[chloro(phenyl)methyl]-2-methoxyquinoline

: 6298-96-0,22038-86-4,35600-82-9,41851-59-6
(S)-1-(4-methoxyphenyl)ethylamine

: 1407513-02-3
(S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

: 1407513-04-5
(S)-N-[(R)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

Guidance literature:: With potassium carbonate; sodium iodide; In acetonitrile; at 20 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201400135

Reference yield: 60.0%

: 110-91-8,99108-56-2
morpholine

: 1407513-02-3
(S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine

: 79-04-9
chloroacetyl chloride

: 1618635-10-1
N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-N-[(S)-1-(4-methoxyphenyl)ethyl]-2-morpholinoacetamide

Guidance literature:: (S)-N-[(S)-(6-bromo-2-methoxy-3-quinolinyl)(phenyl)methyl]-1-(4-methoxyphenyl)ethanamine; chloroacetyl chloride; With triethylamine; In dichloromethane; at -5 - 20 ℃; for 3h;

morpholine; With potassium carbonate; In acetonitrile; at 75 ℃; for 8h;
DOI:10.1002/ejoc.201400135