di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

Base Information

Chemical Name:di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate
CAS No.:1246494-90-5
Molecular Formula:C₂₉H₄₀BFN₄O₇
Molecular Weight:586.469
Hs Code.:

Synonyms:di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

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Chemical Property of di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

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Technology Process of di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

There total 1 articles about di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74124-79-1
di(succinimido) carbonate

: 1027511-51-8
di(tert-butyl) [5-(aminomethyl)pyridin-2-yl]imidodicarbonate

: 819058-34-9
2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

: 1246494-90-5
di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

Guidance literature:: di(succinimido) carbonate; 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; With dmap; In tetrahydrofuran; at 20 ℃; for 18h;

di(tert-butyl) [5-(aminomethyl)pyridin-2-yl]imidodicarbonate; With triethylamine; at 20 ℃; for 5h;

Reference yield: 73.0%

: 1246494-89-2
6-Chloro-2-(ethylamino)-N-(2-hydroxyethyl)nicotinamide

: 1246494-90-5
di(tert-butyl) {5-[({[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl}amino)methyl]pyridin-2-yl}imidodicarbonate

: 1363568-77-7
di(tert-butyl) [5-({[(4-{6-(ethylamino)-5-[(2-hydroxyethyl)carbamoyl]pyridin-2-yl}-2-fluorophenyl)carbamoyl]amino}methyl)pyridin-2-yl]imidodicarbonate

Guidance literature:: With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; ethanol; for 6h; Inert atmosphere; Reflux;