C₅₀H₃₁N₅

Base Information

• Chemical Name: C₅₀H₃₁N₅
• CAS No.: 1415804-07-7
• Molecular Formula: C₅₀H₃₁N₅
• Molecular Weight: 701.83
• Mol file: 1415804-07-7.mol

Synonyms:C₅₀H₃₁N₅

Chemical Property of C₅₀H₃₁N₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₀H₃₁N₅

There total 9 articles about C₅₀H₃₁N₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.5%

5-phenyl-5,11-dihydro-indolo[3,2-b]carbazole (1316311-27-9) + 3-(2-chloroquinazolin-4-yl)-9-phenyl-9H-carbazole (1373317-91-9) → C50H31N5 (1415804-07-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 12h;

Reference yield:

4-Bromophenylboronic acid (5467-74-3) → C50H31N5 (1415804-07-7)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 4 h / 100 °C

2.1: triethyl phosphite / 6 h / 150 °C

3.1: caesium carbonate / copper(l) iodide / toluene / 50 °C

3.2: 14 h / Reflux

4.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C

4.2: 12 h

5.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol / 5 h / Reflux

6.1: triethyl phosphite / 6 h / 150 °C

7.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 12 h / 20 °C

With n-butyllithium; sodium hydride; sodium carbonate; caesium carbonate; triethyl phosphite; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; hexane; N,N-dimethyl-formamide; toluene; mineral oil;

Reference yield:

4'-bromo-2-nitrobiphenyl (35450-34-1) → C50H31N5 (1415804-07-7)

Guidance literature:

Multi-step reaction with 6 steps

1.1: triethyl phosphite / 6 h / 150 °C

2.1: caesium carbonate / copper(l) iodide / toluene / 50 °C

2.2: 14 h / Reflux

3.1: n-butyllithium / hexane; tetrahydrofuran / 1 h / -78 °C

3.2: 12 h

4.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene; ethanol / 5 h / Reflux

5.1: triethyl phosphite / 6 h / 150 °C

6.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 12 h / 20 °C

With n-butyllithium; sodium hydride; sodium carbonate; caesium carbonate; triethyl phosphite; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; hexane; N,N-dimethyl-formamide; toluene; mineral oil;

upstream raw materials:

4-Bromophenylboronic acid

N-phenyl-9H-carbazol-3-boronic acid

2,4-dichloroquinazoline

4'-bromo-2-nitrobiphenyl

Refernces