35450-34-1

Usage

Uses

Used in Organic Synthesis:
4-Bromo-2'-nitrobiphenyl is used as an intermediate in organic synthesis for the production of various chemical compounds. Its presence of bromine and nitro groups allows for further chemical reactions and modifications, making it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
4-Bromo-2'-nitrobiphenyl is used as a key component in the development of pharmaceuticals. Its unique structure and functional groups enable it to be incorporated into drug molecules, potentially leading to the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Bromo-2'-nitrobiphenyl is utilized as a precursor for the synthesis of various agrochemicals, such as pesticides and herbicides. Its chemical properties allow for the creation of compounds that can effectively control pests and weeds, contributing to increased crop yields and agricultural productivity.
Used in Materials Science:
4-Bromo-2'-nitrobiphenyl is also employed in the field of materials science for the development of new materials with specific properties. Its incorporation into polymers and other materials can result in enhanced performance characteristics, such as improved thermal stability, mechanical strength, or electrical conductivity.
It is crucial to handle 4-Bromo-2'-nitrobiphenyl with care, as it may pose risks to human health and the environment. Proper safety measures and disposal methods should be followed to minimize potential hazards.

Upstream product

• 86-00-0 2-nitrobiphenyl 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 1140-28-9 2'-nitro-biphenyl-4-ylamine 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 98-95-3 nitrobenzene 
• 7732-18-5 water 
• 7726-95-6 bromine 
• 7705-08-0 iron(III) chloride 
• 92-52-4 biphenyl 
• 65-85-0 benzoic acid 
• 577-19-5 2-nitrophenyl bromide 
• 5467-74-3 4-Bromophenylboronic acid 
• 108-86-1 bromobenzene 
• 88-74-4 2-nitro-aniline 

Downstream Products

• 586-76-5 4-Bromobenzoic acid 
• 3652-90-2 2-bromo-9H-carbazole 
• 94994-62-4 9-(phenyl)-2-bromo-9H-carbazole 
• 1001911-63-2 (9‐phenyl‐9H‐carbazol‐2‐yl)boronic acid 
• 1361125-94-1 2-(2-nitrophenyl)-9-phenyl-9H-carbazole 
• 1316311-27-9 5-phenyl-5,11-dihydro-indolo[3,2-b]carbazole 
• 1369587-22-3 C₃₀H₁₉BrN₂ 
• 1369587-25-6 C₃₀H₂₁BN₂O₂ 
• 1369585-27-2 C₄₈H₃₀N₂ 
• 56166-63-3 2-bromo-9-ethyl-9H-carbazole 
• 1382955-10-3 9-phenyl-9H,9'H-2,3'-bicarbazole 
• 1393812-52-6 2-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenoxy)-9-(pyridin-2-yl)-9H-carbazole 
• 861025-77-6 2-[4-(2-nitrophenyl)phenyl]pyridine 

Relevant academic research and scientific papers

Single chain white-light-emitting polyfluorene copolymers containing iridium complex coordinated on the main chain

We report the synthesis of single chain white-light-emitting polyfluorene copolymers containing a novel iridium complex with β-diketonate unit, bis(2-benzothiazol-2-yl-N-ethylcarbazole)iridium-l,3bis(p-bromophenyl)l, 3-propanedione ((bec)2IrdbmBr), as the red emission unit. The synthesized polyfluorene copolymers containing the carbazole and iridium complex, poly{9,9-bis(4-octyloxyphenyl)fluorene-2,7-diyl-co(N-hexylcarbazole-3, 6-diyl)-co-[bis(2-benzothiazol-2-yl-N-ethylcarbazole)iridium-l, 3-bis(p-bromophenyl)propanedione-l,3-diyl]} (PFCzIrbecs), were synthesized via palladium-catalyzed Suzuki coupling reactions. These polymers were found to be thermally stable and readily soluble in common organic solvents. Interestingly, the synthesized polymers, PFCzIrbec 05 and PFCzIrbec 2, exhibited two strong emission bands in both the blue and red spectral regions. Light-emitting devices based on these polymers were fabricated in an ITO/PEDOT:PSS/poly(TPD)/polymers/ TPBi/LiF/Al configuration. We obtained white light emission from a single polymer chain by incorporating (bec)2IrdbmBr as the red emission unit into a BOPF and carbazole main chain as the host and blue emission. This device exhibited good performance. In particular, EL device fabricated with PFCzIrbec 2 was found to emit white light consisting of simultaneous blue and red emission with CIE coordinates of (0.31, 0.32), which are close to the standard for white light emission. Moreover, the EL spectrum of PFCzIrbec 2 was stable with respect applied voltage, and CIE coordinates were almost not changed at various driving voltages.

Copper catalysed Gomberg-Bachmann-Hey reactions of arenediazonium tetrafluoroborates and heteroarenediazonium o-benzenedisulfonimides. Synthetic and mechanistic aspects

Gomberg-Bachmann-Hey reactions were carried out in the presence of copper as a catalyst and gave rise to biaryls or heterobiaryls in good yields and in mild reaction conditions. A computational study of some key points of the reaction was performed. The results are coherent with the experimental data and confirm some aspects of the mechanism. The reaction free energies for the reduction in benzene by CuI of a set of 40 (hetero)arenediazonium tetrafluoroborates were calculated. Both the experiments and the calculations showed that in the coupling with substituted solvents (toluene, bromobenzene, nitrobenzene and anisole) the binding to the ortho position was always favoured.

Design, Synthesis, and Pharmacological Characterization of Carbazole Based Dopamine Agonists as Potential Symptomatic and Neuroprotective Therapeutic Agents for Parkinson's Disease

We have developed a series of carbazole-derived compounds based on our hybrid D2/D3 agonist template to design multifunctional compounds for the symptomatic and disease-modifying treatment of Parkinson's disease (PD). The lead molecules (-)-11b (D-636), (-)-15a (D-653), and (-)-15c (D-656) exhibited high affinity for both D2 and D3 receptors and in GTPγS functional assay, the compounds showed potent agonist activity at both D2 and D3 receptors (EC50 (GTPγS); D2 = 48.7 nM, D3 = 0.96 nM for 11b, D2 = 0.87 nM, D3 = 0.23 nM for 15a and D2 = 2.29 nM, D3 = 0.22 nM for 15c). In an animal model of PD, the test compounds exhibited potent in vivo activity in reversing hypolocomotion in reserpinized rats with a long duration of action compared to the reference drug ropinirole. In a cellular antioxidant assay, compounds (-)-11b, (-)-15a, and (-)-15c exhibited potent activity in reducing oxidative stress induced by neurotoxin 6-hydroxydopamine (6-OHDA). Also, in a cell-based PD neuroprotection model, these lead compounds significantly increased cell survival from toxicity of 6-OHDA, thereby producing a neuroprotective effect. Additionally, compounds (-)-11b and (-)-15a inhibited aggregation and reduced toxicity of recombinant alpha synuclein protein in a cell based in vitro assay. These observations suggest that the lead carbazole-based dopamine agonists may be promising multifunctional molecules for a viable symptomatic and disease-modifying therapy of PD and should be further investigated.

COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS

A compound represented by the following formula (1):

Blue light emission of new anthracene derivatives produced using optimized side group link positions

Using an anthracene chromophore as a core group and a phenyl carbazole chromophore as a side group, three new emitters of blue light, 2-DCPA, 3-DCPA and 4-DCPA, were synthesized. The three compounds differed with regard to the position of the carbazole linked to the core, with 2-DCPA and 4-DCPA using carbazole nodes and 3-DCPA using the lobe position. Density functional theory calculations were performed to determine which positions of the carbazole moiety had node characteristics and which had lobe characteristics. The PLmax values of 2-DCPA, 3-DCPA and 4-DCPA in the film state were in the blue region, at 453, 457, and 452 nm, respectively. Of these materials, 3-DCPA, i.e., that with the linkage to the lobe position, showed the highest efficiency, with a value of 2.91 cd/A, and EQE, with a value of 2.65%. In a doped device using CBP as a host material and 3-DCPA as a dopant, the ELmax emission was observed to be in the deep blue region, at 433 nm, and with a CIE value of (0.150, 0.068).

COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

This invention provides a compound for an organic electroluminescent device and an organic electroluminescent device including the same. This invention provides a compound for an organic EL device, which may have high thermal stability, improved light emission efficiency and lifetime and hole transport capability. Further, when this compound is used as a hole transport layer material in contact with a light emitting layer, thereby increasing a triplet energy, ultimately improving efficiency of the organic EL device and lifetime.

Iridium complexes demonstrating broadband emission through controlled geometric distortion and applications thereof

Iridium compounds and their uses are disclosed herein. For example, carbazole containing iridium compounds are disclosed. The compounds are useful in many devices, including, but not limited to, electroluminescent devices.

Synthetic method of 2-bromocarbazole and intermediate thereof

The invention discloses a synthetic method of 2-bromocarbazole and an intermediate thereof. The synthetic method includes the steps of 1) with dichloromethane as a solvent and tert-butyl nitrite as a diazotization reagent, diazotizating o-nitroaniline and performing a coupling reaction to the diazotizated o-nitroaniline and bromobenzene to prepare an intermediate 4-bromo-2'-nitrobiphenyl; 2) adding enough triethyl phosphite to the 4-bromo-2'-nitrobiphenyl to perform a ring closing reaction to the 4-bromo-2'-nitrobiphenyl and the triethyl phosphite; 3) when the ring closing reaction is finished, adding enough hydrochloric acid to damage the triethyl phosphite which is not reacted; and 4) filtering and drying a reaction product to prepare the 2-bromocarbazole.

Organic electroluminescent materials and devices

Novel phosphorescent platinum complexes containing tetradentate ligands are provided. The disclosed compounds have three 6-membered metallocycle units in each tertadentate ligand. The disclosed compounds have desirable electronic properties that make them useful when incorporated into a variety of OLED devices.

Organic electroluminescent materials and devices

Phosphorescent metal complexes comprising a pendant redox-active metallocene are disclosed. These complexes are useful as emitters for phosphorescent OLEDs.