cholest-5-en-3α-ol benzoate

Base Information

• Chemical Name: cholest-5-en-3α-ol benzoate
• CAS No.: 42921-42-6
• Molecular Formula: C₃₄H₅₀O₂
• Molecular Weight: 490.77
• Mol file: 42921-42-6.mol

Synonyms:cholest-5-en-3α-ol benzoate

Chemical Property of cholest-5-en-3α-ol benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of cholest-5-en-3α-ol benzoate

There total 14 articles about cholest-5-en-3α-ol benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

cholesterol mesylate (3381-54-2) + benzoic acid (65-85-0,8013-63-6) → cholest-5-en-3α-ol benzoate (42921-42-6)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; at 95 ℃; for 5h; optical yield given as %ee; enantioselective reaction;

DOI:10.1016/j.tetasy.2009.12.028

Reference yield: 90.0%

epicholesterol (474-77-1) + Benzoyltriazole → cholest-5-en-3α-ol benzoate (42921-42-6)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; for 4h; Ambient temperature;

DOI:10.1021/jo00116a048

Reference yield: 86.0%

cholesterol (57-88-5) + benzoic acid (65-85-0,8013-63-6) → cholest-5-en-3α-ol benzoate (42921-42-6)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In benzene; for 2h; Ambient temperature;

DOI:10.1021/jo00085a037

upstream raw materials:

epicholesterol

benzoyl chloride

cholesterol

benzoic acid

Downstream raw materials:

7-dehydrocholesterol

3α-(benzoyloxy)-5β,6β-epoxy-5β-cholestane