4-methyl-3-nitro-cinnamic acid methyl ester

Base Information

• Chemical Name: 4-methyl-3-nitro-cinnamic acid methyl ester
• CAS No.: 59383-47-0
• Molecular Formula: C₁₁H₁₁NO₄
• Molecular Weight: 221.213
• Mol file: 59383-47-0.mol

Synonyms:4-methyl-3-nitro-cinnamic acid methyl ester

Chemical Property of 4-methyl-3-nitro-cinnamic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-methyl-3-nitro-cinnamic acid methyl ester

There total 4 articles about 4-methyl-3-nitro-cinnamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

4-iodo-2-nitrotoluene (41252-97-5) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → 3,3’-dinitroditoluene (28442-37-7) + 4-methyl-3-nitro-cinnamic acid methyl ester (59383-47-0)

Guidance literature:

With triethylamine; palladium on activated charcoal; In carbon dioxide; at 80 ℃; for 60h; under 75006 Torr;

DOI:10.1055/s-1999-2599

Reference yield: 12.0%

4-iodo-2-nitrotoluene (41252-97-5) → 3,3’-dinitroditoluene (28442-37-7) + 4-methyl-3-nitro-cinnamic acid methyl ester (59383-47-0)

Guidance literature:

With triethylamine; acrylic acid methyl ester; palladium on activated charcoal; In carbon dioxide; at 80 ℃; for 60h; under 75006 Torr;

DOI:10.1055/s-1999-2599

Reference yield:

methanol (67-56-1) + 4-methyl-3-nitro-cinnamic acid (35781-34-1) → 4-methyl-3-nitro-cinnamic acid methyl ester (59383-47-0)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

methanol

4-methyl-3-nitro-cinnamic acid

4-iodo-2-nitrotoluene

acrylic acid methyl ester

Downstream raw materials:

3-(4-methyl-3,5-dinitro-phenyl)-glutaric acid

3-(4-methyl-3,5-dinitro-phenyl)-glutaric acid-anhydride

Refernces